Puerariae Lobatae Radix-Gastrodiae Rhizoma ameliorates nitroglycerin-induced chronic migraine by modulating p38 Mapk/CREB signaling pathway in the prefrontal cortex-thalamus neural circuit
Bibliographic Data
| ID | 14740794 |
|---|---|
| Authors | Zhujun Wang (0000-0002-3998-7477), Zhu‐Jun Wang (0000-0002-8227-7323, Jiangxi University of Traditional Chinese Medicine), Tingting Zhu (0000-0002-2631-3318, Jiangxi University of Traditional Chinese Medicine), Keke Ren (Jiangxi University of Traditional Chinese Medicine), Hui Ouyang (0000-0001-7687-1185, Jiangxi University of Traditional Chinese Medicine, corresponding author), Qihong Pan (0009-0006-9602-9212, Nanchang University, corresponding author), Yuling feng (Jiangxi University of Traditional Chinese Medicine, corresponding author), Shiling Yang (0000-0002-8103-1276, Jiangxi University of Traditional Chinese Medicine) |
| Year | 2026 |
| Volume | 358 |
| Pages | 121043 |
| Publication date | 2026-03-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.121043 |
| PMID | 41397543 |
| OpenAlex | W4417294823 |
| Language | EN |
| Citations received | 2 |
| References cited | 33 |
Biological neural network · Mechanism (biology · Metabolic pathway · Migraine · Neurotransmitter · Prefrontal cortex · Signal transduction · Biological and pharmacological studies of plants · Migraine and Headache Studies · Phytoestrogen effects and research
Investigating the mechanism of Xiongfu formula and its active ingredient Z-Ligustilide alleviates chronic migraine by modulating the Mapk/ERK/CREB pathway and microglia-mediated neuroinflammation
Xiongzhi Qufeng Zhitong Granule alleviates nitroglycerin-induced migraine-like nociception and central neuroinflammation by regulating the HMGB1 / TRPV1 / Mapk signaling axis
| Citations per year | 2 |
|---|---|
| Citation span | 2027 - 2027 (1) |
| Highly cited | No |