Evaluation of You-Gui-Wan critical compounds inhibiting Alox-5 and HDC gene expression in RBL-2H3 cells using a fractional factorial design
Bibliographic Data
| ID | 14741237 |
|---|---|
| Authors | Po-Ting Chen (0000-0002-1856-9815), Po‐Ting Chen (China Medical University), Pei‐Chi Chen (0000-0002-6035-042X, China Medical University), Jiu-Yao Wang, Jiu‐Yao Wang (0000-0003-4540-9822, China Medical University), Shulhn-Der Wang (China Medical University, corresponding author), Li-Jen Lin (0000-0001-7914-9235, China Medical University, corresponding author) |
| Year | 2023 |
| Volume | 305 |
| Pages | 116122 |
| Publication date | 2023-04-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2022.116122 |
| PMID | 36610671 |
| OpenAlex | W4313596630 |
| Language | EN |
| Citations received | 1 |
| References cited | 26 |
The experimental results indicate that YGW exhibits anti-airway hyperresponsiveness and specific immunomodulatory effects. In addition, YGW synergistically inhibits ALOX-5 and HDC gene expression in mast cells through a combination of 21 compounds, including luteolin, quercetin, and β-carotene
Allergy · Antibody · Asthma · Degranulation · Gene · Gene expression · Immune system · Immunoglobulin E · Stimulation · Allergic Rhinitis and Sensitization · Asthma and respiratory diseases · Chemistry · Dermatology and Skin Diseases · Medicine · Biochemistry · Endocrinology · Immunology · Internal Medicine · Pharmacology
| Citations per year | 0.5 |
|---|---|
| Citation span | 2024 - 2024 (1) |
| Highly cited | No |