Formononetin attenuates cerebral ischemia-reperfusion injury by regulating microglial glycolysis through AMPK

Bibliographic Data

ID14741506
AuthorsTianya Zhang (Hebei Medical University, corresponding author), Xiaomeng Dong (0000-0002-2869-7159, Hebei Medical University), Yuqing Zhang (0000-0001-8558-6087, Hebei Medical University), Chaohui Wang (0000-0001-7576-6260, Hebei Medical University), Yaping Tui (Hebei Medical University), Wenting Xu (0000-0002-6671-3308, Hebei Medical University), Bin Wang (0000-0002-8591-8528, Hebei Medical University), Cong Zhang (0000-0002-2561-2113, Hebei Medical University), Xiangjian Zhang (0009-0008-6690-9141, Hebei Medical University, corresponding author)
Year2026
Volume365
Pages121576
Publication date2026-06-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2026.121576
PMID41887382
OpenAlexW7140224617
LanguageEN
References cited35

FN suppresses glycolytic metabolism in microglia through AMPK signaling, thereby influencing microglial polarization and attenuating neuroinflammation

AMPK · Glycolysis · Ischemia · Microglia · Middle cerebral artery · Neuroprotection · Reperfusion injury · Stroke (engine · Western blot · Neuroinflammation and Neurodegeneration Mechanisms · Neurological Disease Mechanisms and Treatments · Traditional Chinese Medicine Analysis

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Open DOIOpen Access