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Astragaloside IV inhibits hepatocellular carcinoma by continually suppressing the development of fibrosis and regulating pSmad3C/3L and Nrf2/HO-1 pathways

Bibliographic Data

ID14742467
AuthorsChong Zhang (0000-0002-3558-2843, Ministry of Education of the People's Republic of China), Lili Li (0000-0002-9793-3995, Ministry of Education of the People's Republic of China), Shu Hou (0000-0001-5303-8596, Ministry of Education of the People's Republic of China), Zhenghao Shi (Ministry of Education of the People's Republic of China), Wenjing Xu (0000-0003-4674-5262, Ministry of Education of the People's Republic of China), Qin Wang (0000-0003-4488-3039, Ministry of Education of the People's Republic of China), Yinghao He (0000-0003-1249-6667, Ministry of Education of the People's Republic of China), Yongfang Gong (Ministry of Education of the People's Republic of China), Zhirui Fang (Ministry of Education of the People's Republic of China), Yan Yang (0000-0001-8648-9692, Ministry of Education of the People's Republic of China, corresponding author)
Year2021
Volume279
Pages114350
Publication date2021-10-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2021.114350
PMID34157326
OpenAlexW3174808242
LanguageEN
Citations received2
References cited43

Apoptosis · Biology · Blot · Cancer · Hepatocellular carcinoma · In vivo · Liver cancer · Metastasis · Pathology · Cancer, Lipids, and Metabolism · Inflammatory mediators and NSAID effects · Medicine · TGF-β signaling in diseases · Biochemistry · Cancer Research · Internal Medicine · Pharmacology

  • Effects and mechanisms of Xiaochaihu Tang against liver fibrosis

    Open Access•Shou-Jia Wang, Wen Ye et al.•Journal of Ethnopharmacology•2023

  • Astragalus membranaceus Fisch. ex Bunge-derived astragaloside IV recovers bilateral cavernous nerve injury-induced erectile dysfunction and corporal fibrosis by inhibiting the TGF-β1/Smad2 pathway in rats

    Open Access•Serhat Sevgi, Irem Cavusoglu Nalbantoglu et al.•Journal of Ethnopharmacology•2026

  • Compound Astragalus and Salvia miltiorrhiza extract suppresses hepatocellular carcinoma progression by inhibiting fibrosis and PAI-1 mRNA transcription

    Open Access•Wenjuan Rui, Lei Xie et al.•Journal of Ethnopharmacology•2014

  • Anti-tumor effects and mechanisms of Astragalus membranaceus (AM) and its specific immunopotentiation

    Open Access•Shanshan Li, Yi Sun et al.•Journal of Ethnopharmacology•2020

  • Compound Astragalus and Salvia miltiorrhiza extract inhibits hepatocellular carcinoma progression via miR-145/miR-21 mediated Smad3 phosphorylation

    Open Access•Chao Wu, Weiyang Chen et al.•Journal of Ethnopharmacology•2019

  • Compound Astragalus and Salvia miltiorrhiza extracts modulate Mapk-regulated TGF-β/Smad signaling in hepatocellular carcinoma by multi-target mechanism

    Open Access•Alex Boye, Chao Wu et al.•Journal of Ethnopharmacology•2015

Unique citing works2
Citations per year0,67
Citation span2023 - 2026 (4)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 2

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