Metabolomics and lipidomics combined with serum pharmacochemistry uncover the potential mechanism of Huang-Lian-Jie-Du decoction alleviates atherosclerosis in ApoE−/− mice
Bibliographic Data
| ID | 14744259 |
|---|---|
| Authors | Xiaoli Yang (0000-0001-7991-1488, Yantai University), Chenglin Chi (Yantai University), Wenjing Li (0000-0003-3631-8435, Yantai University), Yanyan Zhang (0000-0002-0933-3253, Yantai University), Shufang Yang (0000-0002-8818-6297, Yantai University), Ruoxuan Xu (0000-0001-7744-5639, Yantai University), Rongxia Liu (0000-0003-0998-4993, Yantai University, corresponding author) |
| Year | 2024 |
| Volume | 324 |
| Pages | 117748 |
| Publication date | 2024-04-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2024.117748 |
| PMID | 38216103 |
| OpenAlex | W4390706408 |
| Language | EN |
| Citations received | 1 |
| References cited | 48 |
HLJDD improved AS induced by HFD in ApoE -/- mice. The effects of HLJDD were mainly attributed to regulating lipid metabolism by regulating the metabolic pathways of glycerophospholipids, sphingolipids, arachidonic acid, linoleic acid, and glycerolipids and reducing the levels of oxidative stress by upregulating arginine biosynthesis
Biological activity · Chromatography · Decoction · In vitro · Lipidomics · Metabolomics · Pharmacognosy · Traditional medicine · Adipokines, Inflammation, and Metabolic Diseases · Chemistry · Medicine · Metabolomics and Mass Spectrometry Studies · Traditional Chinese Medicine Analysis · Biochemistry · Pharmacology
| Citations per year | 1 |
|---|---|
| Citation span | 2025 - 2025 (1) |
| Highly cited | No |