The anti-tumor effect of OP-B on ovarian cancer in vitro and in vivo, and its mechanism
An investigation using network pharmacology-based analysis
Bibliographic Data
| ID | 14744285 |
|---|---|
| Authors | Shuang Yuan (0000-0003-1383-4023, Sichuan University), Yuanyuan Xu (0000-0001-7147-4498, Sichuan University), Tao Yi (0000-0003-0045-2202, Sichuan University, corresponding author), Hongjing Wang (0000-0002-6235-1231, Sichuan University, corresponding author) |
| Year | 2022 |
| Volume | 283 |
| Pages | 114706 |
| Publication date | 2022-01-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2021.114706 |
| PMID | 34614446 |
| OpenAlex | W3204672018 |
| Language | EN |
| Citations received | 3 |
| References cited | 28 |
OP-B could efficiently suppress OC cellular proliferation, migration and induce apoptosis, cell cycle arrest mainly via the regulation of STAT3 signaling pathway. This study provides a promising potential application for an alternative to chemotherapy in ovarian cancer
Biology · Cancer · Gene · Gene expression · In vitro · In vivo · KEGG · Ovarian cancer · Transcriptome · Western blot · Medicine · Natural product bioactivities and synthesis · Phytochemical Studies and Bioactivities · Phytochemistry and Bioactive Compounds · Biochemistry · Internal Medicine · Pharmacology
Phytochemical determination and mechanistic investigation of Polygala tenuifolia root (Yuanzhi) extract for bronchitis
The potential of natural herbal plants in the treatment and prevention of non-small cell lung cancer
Regulatory mechanisms of signaling pathways in liver cancer treatment with traditional Chinese medicine
| Unique citing works | 3 |
|---|---|
| Citations per year | 1,5 |
| Citation span | 2024 - 2025 (2) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 3 |