Exploring the potential targets of Sanshimao formula for hepatocellular carcinoma treatment by a method of network pharmacology combined with molecular biology

Bibliographic Data

ID14744660
AuthorsYu Qin (0000-0002-8973-8540, Yueyang Hospital), Qin Yu (0000-0002-4342-9398), Zhe Chen (0000-0003-3194-2933, Second Military Medical University), Minglin Liu, Ming‐Lin Liu (0000-0001-8827-2024, Second Military Medical University), Yongbin Meng (0000-0001-8088-1415, Second Military Medical University), Xiaoyan Li (0000-0001-5383-1236, Second Military Medical University), Bai Li (0009-0005-5729-9685, Second Military Medical University, corresponding author), Juan Du (0000-0001-7846-1905, Second Military Medical University, corresponding author)
Year2022
Volume297
Pages115531
Publication date2022-10-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2022.115531
PMID35840058
OpenAlexW4285605484
LanguageEN
Citations received1
References cited53

This research preliminarily indicates that SSM treats HCC via multiple components and pathways. EGFR/FAK/AKT are promising therapeutic targets of SSM for HCC treatment. This provides objective evidence for further mechanistic research and the future development and clinical application of SSM in HCC patients

Apoptosis · Biology · Computational biology · Hepatocellular carcinoma · PI3K/AKT/mTOR pathway · Protein kinase B · Signal transduction · Signalling pathways · Computational Drug Discovery Methods · Medicine · Natural product bioactivities and synthesis · Traditional Chinese Medicine Analysis · Biochemistry · Cancer Research · Pharmacology

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Open DOIOpen Access