Yiqi Kaimi prescription regulates protein phosphorylation to promote intestinal motility in slow transit constipation

Bibliographic Data

ID14744789
AuthorsYi-Bo Yao, Yibo Yao (0000-0001-5317-3974, Longhua Hospital Shanghai University of Traditional Chinese Medicine, corresponding author), Chang-Fang Xiao (0000-0003-4678-6435, Longhua Hospital Shanghai University of Traditional Chinese Medicine), Jingwen Wu (0000-0003-0939-511X, Longhua Hospital Shanghai University of Traditional Chinese Medicine), Jing-Wen Wu, Ling-Yun Meng, Lingyun Meng (0009-0007-9646-6081, Shanghai University of Traditional Chinese Medicine), Wei Liu (0000-0002-5949-0302, Shuguang Hospital), Jin-gen Lu, Jingen Lu (0000-0003-2640-3775, Longhua Hospital Shanghai University of Traditional Chinese Medicine), Chen Wang (0000-0003-3042-291X, Longhua Hospital Shanghai University of Traditional Chinese Medicine, corresponding author)
Year2024
Volume329
Pages118118
Publication date2024-07-01
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2024.118118
PMID38614261
OpenAlexW4394796254
LanguageEN
Citations received1
References cited68

Yiqi Kaimi prescription significantly enhanced intestinal motility. This effect was attributed to alterations in the phosphorylation levels of various target proteins. The observed changes in protein phosphorylation, including SYK and RELA, may serve as crucial factors in the treatment of slow transit constipation

Biology · Constipation · Medical prescription · Motility · Phosphorylation · Tyrosine phosphorylation · Western blot · Gastrointestinal motility and disorders · Gut microbiota and health · Medicine · Microbial Metabolites in Food Biotechnology · Biochemistry · Cancer Research · Cell Biology · Endocrinology · Internal Medicine · Pharmacology

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