Integrated serum metabolomics, 16S rRNA sequencing and bile acid profiling to reveal the potential mechanism of gentiopicroside against nonalcoholic steatohepatitis in lean mice
Bibliographic Data
| ID | 14745845 |
|---|---|
| Authors | Zeyun Li (0000-0001-8773-1962, Zhengzhou University, corresponding author), Xueya Zhu (Zhumadian Central Hospital), Chenhao Li (0000-0002-8649-1263, First Affiliated Hospital of Zhengzhou University), Ruiting Tang (First Affiliated Hospital of Zhengzhou University), Yuanyuan Zou (0000-0003-1242-7936, Yichun University), Shuaibing Liu (0000-0003-1577-1310, Zhengzhou University, corresponding author) |
| Year | 2024 |
| Volume | 334 |
| Pages | 118526 |
| Publication date | 2024-11-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2024.118526 |
| PMID | 38972531 |
| OpenAlex | W4400363706 |
| Language | EN |
| References cited | 64 |
GPS may ameliorate steatosis in lean mice with NASH, regulating the metabolomic profile, BA metabolism, fatty acid biosynthesis, and BA-related GM. All these factors may contribute to its beneficial effect
Bioinformatics · Biology · Computational biology · Fatty liver · Mechanism (biology · Metabolomics · Nonalcoholic fatty liver disease · Nonalcoholic steatohepatitis · Steatohepatitis · Traditional medicine · Chemistry · Liver Disease Diagnosis and Treatment · Medicinal Plants and Bioactive Compounds · Medicine · Phytochemistry and Biological Activities · Internal Medicine · Pharmacology
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| Citation velocity | historical |
|---|---|
| Highly cited | No |