Potential anti-gastric cancer properties of modified Lichong decoction based on metabolomics, network pharmacology, and pharmacological verification
Bibliographic Data
| ID | 14745944 |
|---|---|
| Authors | Guoshan Shi, Guanglu Shi (0000-0001-5562-111X, Guiyang Medical University), Zhe Chen (0000-0003-3194-2933, Qiqihar Medical University), Meiyu Feng (Heilongjiang Provincial Hospital), Hongyu Yao (0000-0002-6626-2682, Qiqihar Medical University), Yujing Wang (0000-0001-8119-5142, Qiqihar Medical University), Liwei Ma (0009-0001-9359-4906, Qiqihar Medical University, corresponding author) |
| Year | 2025 |
| Volume | 347 |
| Pages | 119806 |
| Publication date | 2025-05-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2025.119806 |
| PMID | 40233887 |
| OpenAlex | W4409424360 |
| Language | EN |
| Citations received | 1 |
| References cited | 37 |
This study evaluated the pharmacological effects of MLCD on gastric cancer. These results suggest that MLCD can exert an anti-gastric cancer effects through multiple targets and pathways and that the PI3k/Akt pathway is an important pathway in the regulation of proliferation, cell cycle, and apoptosis in gastric cancer. The toxic effects of MLCD on tumour-bearing mice were indistinctively observed after continuous administration for 4 weeks
Alternative medicine · Biological activity · Cancer · Decoction · In vitro · Pharmacognosy · Traditional Chinese medicine · Traditional medicine · Cancer-related molecular mechanisms research · Chemistry · Ginseng Biological Effects and Applications · Medicinal Plant Pharmacodynamics Research · Medicine · Biochemistry · Internal Medicine · Pharmacology
| Unique citing works | 1 |
|---|---|
| Citations per year | 1 |
| Citation span | 2025 - 2025 (1) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 1 |