Immunomodulatory effects and mechanisms of Tiepishihu Xiyangshen granules on cyclophosphamide induced immuno-suppression via TLR4/Mapks and PI3K/AKT/Foxo3a signal pathways

Bibliographic Data

ID14746314
AuthorsNan Hu (0000-0003-4866-4263, Shenyang Pharmaceutical University), Yue Qu (0000-0002-1912-4623, Shenyang Pharmaceutical University), Tingyu Liu (0000-0001-8934-6611, Shenyang Pharmaceutical University), Ting-yu Liu, Yue Zhou (0009-0009-2070-9715, Harbin Medical University), Chang Liu (0000-0002-1198-6990, Harbin Medical University), Jin-hui Wang (0000-0001-8340-717X), Jinhui Wang (0000-0003-3201-707X, Harbin Medical University), Bao-Feng Yang, Baofeng Yang (0000-0002-0125-1608, Shenyang Pharmaceutical University, corresponding author), Chun-Li Li (Shenyang Pharmaceutical University, corresponding author), Chunli Li (0000-0003-1259-7089)
Year2023
Volume307
Pages116192
Publication date2023-05-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2023.116192
PMID36706933
OpenAlexW4317933665
LanguageEN
References cited38

The results of this study confirmed that TXG has prominent immunomodulatory activities, and the immunity regulations of TXG may be achieved by regulating TLR4/MAPKs and PI3K/AKT/FOXO3a signal pathways

Biology · Immune system · Immunosuppression · Lymphocyte · Protein kinase B · Signal transduction · Spleen · Biological and pharmacological studies of plants · Ginseng Biological Effects and Applications · Immune Cell Function and Interaction · Medicine · Cell Biology · Immunology · Pharmacology

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