Detection and isolation of intestinal muscle relaxant substances from the root of Taverniera abyssinica A. Rich
Bibliographic Data
| ID | 14746757 |
|---|---|
| Authors | Daniel Seifu (0000-0003-1490-4441, Karolinska Institutet), Kristofer F Nilsson (0000-0002-8461-5074, Örebro University), Rajinder Chawla (Addis Ababa University), Solomon Genet (0000-0002-5433-0107, Addis Ababa University), Mikael Holst (Uppsala University), Asfaw Debella (0000-0003-1666-1578, Ethiopian Public Health Institute), Per M Hellström (0000-0001-8428-0772, Uppsala University, corresponding author) |
| Year | 2023 |
| Volume | 312 |
| Pages | 116498 |
| Publication date | 2023-08-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Journal of Ethnopharmacology (JOURNAL) |
| Journal identifiers | ISSN: 0378-8741 • E-ISSN: 1872-7573 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.jep.2023.116498 |
| PMID | 37059252 |
| OpenAlex | W4365452704 |
| Language | EN |
| References cited | 14 |
The traditionally claimed smooth muscle-relaxing effect of the roots of Taverniera abyssinica A.Rich is essentially due the three isolated and purified the two isoflavones formononetin, afrormosin as well as the metoxyisoflavone tectorigenin, along with possibly other not yet purified bioactive substances, however with similar smooth muscle-relaxing properties
Bioassay · Biological activity · Biology · Chromatography · Formononetin · Fractionation · Guinea pig · High-performance liquid chromatography · Ileum · In vitro · Traditional medicine · Chemistry · Medicine · Natural Antidiabetic Agents Studies · Natural product bioactivities and synthesis · Pharmacological Effects of Natural Compounds · Biochemistry
| Citation velocity | historical |
|---|---|
| Highly cited | No |