A brick to a bundle
A qualitative study of behavioral responses to xylazine adulteration
Bibliographic Data
| ID | 14908574 |
|---|---|
| Authors | Adams L Sibley (0000-0001-5073-8677, University of North Carolina at Chapel Hill, corresponding author), Colin Miller (University of North Carolina at Chapel Hill), Colin W Miller, Elizabeth Joniak-Grant (0000-0001-8260-485X, University of North Carolina at Chapel Hill), Alice Bell (0000-0001-9737-4081, Center Point), Malcolm Visnich (Center Point), Steve Alsum (Grand Rapids Community College), Nilanjana Dasgupta (0000-0002-4098-605X, University of North Carolina at Chapel Hill), Nabarun Dasgupta |
| Year | 2025 |
| Volume | 145 |
| Pages | 105017 |
| Publication date | 2025-11-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Drug Policy (JOURNAL) |
| Journal identifiers | ISSN: 0955-3959 • E-ISSN: 1873-4758 |
| Publisher | Elsevier BV (PUBLISHER) |
| DOI | 10.1016/j.drugpo.2025.105017 |
| PMID | 41016250 |
| OpenAlex | W4414569117 |
| Language | EN |
| References cited | 51 |
Findings suggest that people who use drugs are adapting consumption patterns and adopting harm reduction practices as coping responses to xylazine's adverse effects. Unlike previous major opioid market transitions that primarily differed in pharmacokinetics, xylazine introduces new risks while replacing desired psychoactive effects with undesirable ones. The widespread dissatisfaction with xylazine represents a unique opportunity to expand harm reduction interventions and explore safe supply policies while risk salience is high and user motivation for safer practices aligns with public health goals
Coping (psychology · Harm · Harm reduction · Psychological intervention · Public health interventions · Qualitative research · SAFER · Salience (neuroscience · Xylazine · Forensic Toxicology and Drug Analysis · Opioid Use Disorder Treatment · Veterinary Pharmacology and Anesthesia
The Future of Deadly Synthetic Opioids
Tackling the overdose crisis
Drug use behaviors, trauma, and emotional affect following the overdose of a social network member
Ethical justifications for safe supply interventions
A rapid review of the impacts of “Big Events ” on risks, harms, and service delivery among people who use drugs
The protective effect of trusted dealers against opioid overdose in the U.S
A content analysis of legal policy responses to xylazine in the illicit drug supply in the United States
Spatiotemporal Analysis Exploring the Effect of Law Enforcement Drug Market Disruptions on Overdose, Indianapolis, Indiana, 2020–2021
Risk environments and drug harms
Potency-Enhancing Synthetics in the Drug Overdose Epidemic
Rapid and Rigorous Qualitative Data Analysis
| Citation velocity | historical |
|---|---|
| Highly cited | No |