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Evaluación rápida del impacto de la vacuna contra Haemophilus influenzae serotipo b en Colombia

Bibliographic Data

ID14965816
AuthorsClara Inés Agudelo (0000-0002-9242-3910, corresponding author), Nélida Muñoz (0000-0002-9662-2554, Instituto Nacional de Salud), Fernando De La Hoz (0000-0001-9436-7935, Instituto Nacional de Salud)
Year2000
Volume8
Issue3
Pages181-184
Publication date2000-09-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueRevista Panamericana de Salud Pública (JOURNAL)
Journal identifiersISSN: 1020-4989 • E-ISSN: 1680-5348
PublisherFapUNIFESP (SciELO) (PUBLISHER)
DOI10.1590/s1020-49892000000800005
PMID11036428
OpenAlexW2111536522
SCIELO_PIDS1020-49892000000800005
LanguageES
Citations received2
References cited2

In May 1998 the Ministry of Health of Colombia started a universal vaccination campaign against Haemophilus influenzae type b (Hib) for children under one year of age. The impact of this intervention on the incidence of acute bacterial meningitis was assessed in 1999, using data from the laboratory-based surveillance system coordinated since 1994 by the Microbiology Group of the Colombian National Institute of Health. The analysis compared the annual number of cases of Hib meningitis in children under one year of age diagnosed through the surveillance system before the vaccine was introduced with the number of cases reported during the first year after the vaccine's introduction. The expected number of cases, given the average annual number of cases diagnosed between June 1994 and June 1998, was compared with the number of cases observed after the vaccination program was introduced, from June 1998 through May 1999. To control for the quality of the surveillance system, a similar analysis was done for cases of meningitis due to Streptococcus pneumoniae. The analysis was restricted to those departments of Colombia that had consistently participated in the surveillance system. For the years 1994 through 1998 the numbers of confirmed cases of Hib meningitis were, respectively, 45, 37, 61, 64, and 31. In the period after the vaccine's introduction 31 cases were observed, as compared to the 52 expected (P < 0.001). During the same annual periods there were 32, 26, 43, 48, and 42 confirmed cases of meningitis from S. pneumoniae in children less than 5 years old, showing no significant reduction in the expected number of those cases. The 40% decrease noted in Hib meningitis cases was not attributable to changes in the surveillance system and was due mainly to the effects of the vaccination program

Antibiotics · Biology · Christian ministry · Conjugate vaccine · Haemophilus influenzae · Hib vaccine · Immunization · Incidence (geometry · Meningitis · Streptococcus pneumoniae · Vaccination · Bacterial Infections and Vaccines · Influenza Virus Research Studies · Medicine · Pneumonia and Respiratory Infections · Immunology · Microbiology · Pediatrics · Virology

  • Impacto de la vacunación contra Haemophilus influenzae tipo b en Cuba

    Open Access•Félix O Dickinson, Félix Dickinson et al.•Revista Panamericana de Salud…•2001

  • Incidência de meningite por Haemophilus influenzae no RS 1999-2010

    Open Access•João Guilherme Stadler Schossler, Sandra Trevisan Beck et al.•Ciência & Saúde Coletiva•2013

  • Vacunación contra Haemophilus influenzae tipo b en el Uruguay

    Open Access•Gloria Ruocco, Sergio Curto et al.•Revista Panamericana de Salud…•1999

  • Introducción de la vacuna conjugada contra Hib en Chile y Uruguay

    Open Access•Mauricio Landaverde, José Luis Di Fábio et al.•Revista Panamericana de Salud…•1999

Unique citing works2
Citations per year0,08
Citation span2001 - 2013 (13)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 2

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