Individual deprivation, regional deprivation, and risk for oral clefts in Argentina

Bibliographic Data

ID14967413
AuthorsMariela Pawluk (0000-0001-6306-0842, Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno, corresponding author), Mariela Soledad Pawluk (Buenos Aires), Hebe Campaña (0000-0002-2330-5267, Estudios Clínicos Latinoamérica), Mónica Rittler (0000-0002-0840-7548, Estudio Colaborativo Latinoamericano de Malformaciones Congénitas (ECLAMC), Hospital Materno Infantil Ramón Sarda, Buenos Aires, Argentina.), Fernando Poletta (0000-0002-6102-8416, Estudios Clínicos Latinoamérica), Fernando Adrián Poletta, Viviana Cosentino (0000-0002-6708-9658, Estudios Clínicos Latinoamérica), Viviana R Cosentino, Juan Gili (0000-0001-7924-0776, Estudios Clínicos Latinoamérica), Juan Antonio Gili, Lucas Gimenez (0000-0001-9991-3843, Estudios Clínicos Latinoamérica), Lucas Gabriel Gimenez, Jorge S López Camelo (0000-0002-3146-5447, Estudios Clínicos Latinoamérica)
Year2017
Volume41
Pages1
Publication date2017-10-12
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueRevista Panamericana de Salud Pública (JOURNAL)
Journal identifiersISSN: 1020-4989 • E-ISSN: 1680-5348
PublisherPan American Health Organization (PUBLISHER • US)
DOI10.26633/rpsp.2017.110
PMID29466515
OpenAlexW2762482121
LanguageEN
Citations received2
References cited30

Objective. The aim of this study was to analyze the effects of individual low socioeconomic status (SES) and deprived geographical area (GA) on the occurrence of isolated cleft lip with or without cleft palate (CL±P) in Argentina . Methods. This case-control study included 577 newborns with isolated CL±P and 13 344 healthy controls, born between 1992 and 2001, from a total population of 546 129 births in 39 hospitals in Argentina. Census data on unsatisfied basic needs were used to establish the degree of geographical area deprivation. An SES index for each individual was established, using maternal age, gravidity, low paternal and maternal education, and low-level paternal occupation. Logistic regression was used to assess the effects of low SES and of deprived GA on CL±P . Results. A slightly increased risk of CL±P was observed in mothers with a low SES, while a deprived GA showed no effect. Native ancestry, acute maternal illnesses, and poor prenatal care were significant risk factors for CL±P for the mothers with low SES, after using propensity scores to adjust for the demographic characteristics in cases and controls . Conclusions. Low individual SES slightly increased the risk for CL±P, but a deprived GA did not have that effect. There was no interaction between individual SES and deprived GA. Factors related to low individual SES—including poor prenatal care, low parental education, lack of information, and lifestyle factors—should be primarily targeted as risk factors for CL±P rather than factors related to a deprived place of residence

Logistic regression · Population · Social deprivation · Socioeconomic status · Cleft Lip and Palate Research · Demography · Dental Health and Care Utilization · Food Security and Health in Diverse Populations · Medicine · Psychology · Pediatrics