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The landscape of Covid-19 clinical trials in Latin America and the Caribbean

Assessment and challenges

Bibliographic Data

ID14967776
AuthorsSarah Carracedo (0000-0002-3995-6793, Pan American Health Organization, Washington, DC, United States of America., corresponding author), Ana Palmero (0000-0002-5781-9071, Pan American Health Organization, Washington, DC, United States of America.), Marcie Neil (Pan American Health Organization, Washington, DC, United States of America.), Anisa Hasan-Granier (Pan American Health Organization, Washington, DC, United States of America.), Carla Saénz (0000-0002-2040-9423, Pan American Health Organization, Washington, DC, United States of America.), Ludovic Reveiz (0000-0003-3186-9174, Pan American Health Organization, Washington, DC, United States of America.)
Year2020
Volume44
Pages1
Publication date2020-12-23
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueRevista Panamericana de Salud Pública (JOURNAL)
Journal identifiersISSN: 1020-4989 • E-ISSN: 1680-5348
PublisherPan American Health Organization (PUBLISHER • US)
DOI10.26633/rpsp.2020.177
PMID33406166
OpenAlexW3117036247
LanguageEN
Citations received2
References cited5

A considerable number of clinical trials is being conducted globally in response to the COVID-19 pandemic, including in low- and middle-income countries such as those in the Latin America and Caribbean region (LAC). Yet, an abundance of studies does not necessarily shorten the path to find safe and efficacious interventions for COVID-19. We analyze the trials for COVID-19 treatment and prevention that are registered from LAC countries in the International Clinical Trials Registry Platform, and identify a trend towards small repetitive non-rigorous studies that duplicate efforts and drain limited resources without producing meaningful conclusions on the safety and efficacy of the interventions being tested. We further assess the challenges to conducting scientifically sound and socially valuable research in the LAC region in order to inform recommendations to encourage clinical trials that are most likely to produce robust evidence during the pandemic

Clinical trial · Coronavirus disease 2019 (COVID-19 · Geography · Latin Americans · Pandemic · Pathology · Political science · Psychological intervention · COVID-19 and healthcare impacts · COVID-19 Clinical Research Studies · Medicine · Nursing · SARS-CoV-2 and COVID-19 Research

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    Open Access•Carla Saénz, Timothy Krahn et al.•BMJ Global Health•2024

  • Mapeo de protocolos de investigación, publicaciones y colaboraciones sobre la Covid-19 en América Latina y el Caribe

    Open Access•Evelina Chapman, Eduardo Illanes et al.•Revista Panamericana de Salud…•2022

  • Adherence to clinical trial registration in countries of Latin America and the Caribbean, 2015

    Open Access•Pilar García-Vello, Emma Smith et al.•Revista Panamericana de Salud…•2018

Unique citing works2
Citations per year0,5
Citation span2022 - 2024 (3)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 2

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Open DOIOpen Access
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