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Variação na detecção da síndrome congênita do Zika em função de alterações em protocolos

Bibliographic Data

ID14968547
AuthorsHelaine Jacinta Salvador Mocelin (0000-0001-9789-9670, Universidade Federal do Espírito Santo (UFES), Laboratório de Epidemiologia (Lab-Epi), Vitória (ES), Brasil., corresponding author), Thiago Nascimento Do Prado (0000-0001-8132-6288, Universidade Federal do Espírito Santo (UFES), Laboratório de Epidemiologia (Lab-Epi), Vitória (ES), Brasil.), Paula De Souza Silva Freitas (0000-0001-9066-3286, Universidade Federal do Espírito Santo (UFES), Laboratório de Epidemiologia (Lab-Epi), Vitória (ES), Brasil.), Adelmo Inácio Bertolde (0000-0002-1747-9957, Universidade Federal do Espírito Santo (UFES), Departamento de Estatística, Vitória (ES), Brasil.), Federico Pérez (0000-0003-2001-0057, Pan American Health Organization (Brasil)), Freddy Pérez (Organização Pan-Americana da Saúde (OPAS), Departamentos de Doenças Transmissíveis e Determinantes Ambientais da Saúde, Washington (DC), Estados Unidos.), Lee W Riley (0000-0001-9916-3894, Universidade da Califórnia, Escola de Saúde Pública, Divisão de Doenças Infecciosas e Vacinologia, Berkeley (CA), Estados Unidos.), Ethel Leonor Noia Maciel (0000-0003-4826-3355, Universidade Federal do Espírito Santo (UFES), Laboratório de Epidemiologia (Lab-Epi), Vitória (ES), Brasil.)
Year2019
Volume43
Pages1
Publication date2019-09-20
Open AccessYes
TypeARTICLE
VenueRevista Panamericana de Salud Pública (JOURNAL)
Journal identifiersISSN: 1020-4989 • E-ISSN: 1680-5348
PublisherPan American Health Organization (PUBLISHER • US)
DOI10.26633/rpsp.2019.79
PMID31579398
OpenAlexW2973299530
LanguagePT
Citations received2
References cited8

In 2015, Brazil faced a Zika virus epidemic that spread to other countries in the world. As a result, recommendations regarding reporting criteria for congenital Zika syndrome (CZS) were issued in the form of protocols. The frequent changes in these recommendations may have affected clinical management and the access to post-diagnostic support by children who were affected by CZS, but who ended up not being identified. In the present study, 39 cases of CZS reported in the state of Espírito Santo, Brazil, from 2015 to 2016 were re-classified in terms of diagnosis using the current protocol, which is different from the protocol used in 2015. According to this re-classification, only eight out of 36 cases would be confirmed, based on the criterion of two or more signs or symptoms of CZS with or without microcephaly plus positive serologic results. Also, considering the decrease in the head circumference cut-off point defining microcephaly, 17 cases would no longer meet the definition for this condition. Even though the current protocol does not rely on head circumference alone for CZS reporting and confirmation, it should be noted that this is still the main sign considered by health care teams, and therefore the decrease in the cut-off point might have compromised early CZS detection. A review of "ruled out" cases would be advisable in moments of protocol transition to determine whether these cases have been correctly classified

Alternative medicine · Head circumference · Humanities · Microcephaly · Pathology · Pregnancy · Protocol (science · Virus · Zika virus · Medicine · Mosquito-borne diseases and control · Syphilis Diagnosis and Treatment · Virology and Viral Diseases · Pediatrics · Virology

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Citations per year0.33
Citation span2020 - 2022 (3)
Highly citedNo

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