Association between Light-Intensity and Moderate-to-Vigorous-Intensity Physical Activity Habits and Kidney Dysfunction

A General Population Cohort Study

Bibliographic Data

ID15087180
AuthorsGoro Sakurai (0000-0002-9153-351X, Kanazawa University Hospital), Tadashi Toyama (0000-0003-0162-6286, Kanazawa University, corresponding author), Toshiaki Tokumaru (0009-0006-5323-0688, Kanazawa University), Akinori Hara (0000-0002-0399-1474, Kanazawa University), Yuta Yamamura (0000-0003-3713-0733, Kanazawa University), Shiori Nakagawa (0000-0001-6774-7959, Kanazawa University), Megumi Oshima (0000-0002-4108-5229, Kanazawa University), Taro Miyagawa (0000-0003-0186-7362, Kanazawa University), Hisayuki Ogura (0000-0001-9004-3837, Kanazawa University), Shinji Kitajima (0000-0002-6532-6496, Kanazawa University), Norihiko Sakai (0000-0001-7245-9716, Kanazawa University), Miho Shimizu (0000-0002-7737-935X, Kanazawa University), Takashi Wada (0000-0002-0123-3645, Kanazawa University), Yasunori Iwata (0000-0002-4756-5207, Kanazawa University)
EditorsTommaso Martino (0000-0001-8877-4104)
Year2023
Volume2023
Pages1-8
Publication date2023-05-27
Open AccessYes
TypeARTICLE
VenueHealth & Social Care in the Community (JOURNAL)
Journal identifiersISSN: 0966-0410 • E-ISSN: 1365-2524
PublisherWiley (PUBLISHER • GB)
DOI10.1155/2023/9677484
OpenAlexW4378576259
LanguageEN
References cited35

Few studies have considered physical activity (PA) intensity and frequency in relation to kidney dysfunction. This study aimed to investigate the association of regular light intensity, occasional moderate-to-vigorous physical activities, and their combination with kidney function in the general population. This community-based historical cohort study included Japanese people aged ≥40 years. Participants were divided into four groups according to their PA habits: inactive group (neither regular light-intensity physical activity (LPA) nor occasional moderate-to-vigorous physical activity (MVPA)), LPA group (1.5–3.0 metabolic equivalents (METs) for at least 60 min a day), MVPA group (>3.0 METs for at least 30 min twice a week), and LPA + MVPA group (combination of LPA and MVPA). The primary outcome was a 40% decrease in the estimated glomerular filtration rate from the baseline. The Cox proportional hazards model was used to examine the association between PA habits and kidney function. In total, 72,999 participants were included in this study. During the mean follow-up period of 5.9 years, 2,989 (4.1%) participants achieved the outcome. Compared to participants with neither LPA nor MVPA, the adjusted hazard ratios were 0.94 (95% confidence interval (CI), 0.85–1.03; p = 0.182 ) for LPA alone, 0.97 (95% CI, 0.85–1.10; p = 0.618 ) for MVPA alone, and 0.83 (95% CI, 0.76–0.91; p 0.001 ) for a combination of LPA and MVPA. There was a significant interaction between sex and PA habit ( p = 0.015 ). Generally, combined LPA and MVPA were associated with a lower risk of kidney dysfunction than was the lack of PA. Future studies are required to determine the PA intensity and duration required to protect kidney function

Cohort · Cohort study · Confidence interval · Hazard ratio · Intensity (physics) · Metabolic equivalent · Physical activity · Physical therapy · Physics · Population · Proportional hazards model · Renal function · Demography · Dialysis and Renal Disease Management · Internal Medicine · Medicine · Obesity, Physical Activity, Diet · Physical Activity and Health · Gerontology

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