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Higher Healthy Lifestyle Score is associated with lower presence of non-alcoholic fatty liver disease in middle-aged and older Chinese adults

A community-based cross-sectional study

Bibliographic Data

ID15090796
AuthorsYun-yang Deng, Yunyang Deng (0000-0003-4848-2953, Sun Yat-sen University), Qing-wei Zhong (0000-0001-5485-2557, Sun Yat-sen University), Hai-li Zhong, Haili Zhong (Sun Yat-sen University), Feng Xiong (0000-0003-4165-3385, Sun Yat-sen University), Yue-bin Ke, Yuebin Ke (0000-0003-1104-1898, Shenzhen Center for Disease Control and Prevention, corresponding author), Yu‐Ming Chen (0000-0003-1658-5528, Sun Yat-sen University, corresponding author)
Year2021
Volume24
Issue15
Pages5081-5089
Publication date2021-10-01
Open AccessYes
TypeARTICLE
VenuePublic Health Nutrition (JOURNAL)
Journal identifiersISSN: 1368-9800 • E-ISSN: 1475-2727
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1368980021000902
PMID33634772
OpenAlexW3131159569
LanguageEN
Citations received4
References cited32

Objective: Previous studies have reported inverse associations between certain healthy lifestyle factors and non-alcoholic fatty liver disease (NAFLD), but limited evidence showed the synergistic effect of those lifestyles. This study examined the relationship of a combination of lifestyles, expressed as Healthy Lifestyle Score (HLS), with NAFLD. Design: A community-based cross-sectional study. Questionnaires and body assessments were used to collect data on the six-item HLS (ranging from 0 to 6, where higher scores indicate better health). The HLS consists of non-smoking (no active or passive smoking), normal BMI (18·5–23·9 kg/m 2 ), physical activity (moderate or vigorous physical activity ≥ 150 min/week), healthy diet pattern, good sleep (no insomnia or Setting: Guangzhou, China. Participants: Two thousand nine hundred and eighty-one participants aged 40–75 years. Results: The overall prevalence of NAFLD was 50·8 %. After adjusting for potential covariates, HLS was associated with lower presence of NAFLD. The OR of NAFLD for subjects with higher HLS (3, 4, 5–6 v . 0–1 points) were 0·68 (95 % CI 0·51, 0·91), 0·58 (95 % CI 0·43, 0·78) and 0·35 (95 % CI 0·25, 0·51), respectively ( P -values Conclusions: Higher HLS was associated with lower presence of NAFLD, suggesting that a healthy lifestyle pattern might be beneficial to liver health

Anxiety · Cross-sectional study · Disease · Fatty liver · Psychiatry · Diet, Metabolism, and Disease · Liver Disease and Transplantation · Liver Disease Diagnosis and Treatment · Medicine · Internal Medicine

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Citations per year1.33
Citation span2023 - 2025 (3)
Highly citedNo

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