Iron status in late pregnancy is inversely associated with birth weight in Colombia
Bibliographic Data
| ID | 15091983 |
|---|---|
| Authors | Alejandra Puerto (0000-0001-5877-2001, University of Cartagena), Annabelle Trojan (University of Cartagena), Nelson Rafael Alvis-Zakzuk, Rossana López-Saleme, Rossana López Sáleme (0000-0003-0661-775X, University of Cartagena), Francisco Edna-Estrada (0000-0001-9439-2540), Álvaro Pérez Álvarez (0000-0002-6936-4887, University of Cartagena), Álvaro Álvarez (0000-0003-3648-357X), Nelson Alvis-Guzman (0000-0001-9458-864X, University of the Coast), Josefina Zakzuk (0000-0002-6007-5376, University of Cartagena, corresponding author) |
| Year | 2021 |
| Volume | 24 |
| Issue | 15 |
| Pages | 5090-5100 |
| Publication date | 2021-10-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Public Health Nutrition (JOURNAL) |
| Journal identifiers | ISSN: 1368-9800 • E-ISSN: 1475-2727 |
| Publisher | Cambridge University Press (CUP) (PUBLISHER) |
| DOI | 10.1017/s136898002100166x |
| PMID | 33860744 |
| OpenAlex | W3154522248 |
| Language | EN |
| References cited | 53 |
Objective: Gestational anaemia (GA) is common in developing countries. This study assessed the relationship of late GA and negative perinatal outcomes in participants recruited in a reference maternity unit of the Caribbean region of Colombia. Design: Prospective analytical birth cohort study. Maternal Hb and serum ferritin (SF) levels were measured. GA was defined as Hb levels Setting: Mothers in the first stage of labour, living in urban or rural areas of Bolívar, were enrolled in an obstetrical centre located in Cartagena, Colombia. Blood and stool samples were taken prior delivery. Maternal blood count, SF levels and infant anthropometric data were recorded for analysis. Participants: 1218 pregnant women aged 18–42 years and their newborns. Results: Prevalence of GA and SF depletion was 41·6 % and 41·1 %, respectively. GA was positively associated with poverty-related sociodemographic conditions. Prenatal care attendance lowered the risk of PB, LBW and SGA. Birth weight was inversely associated with Hb levels, observing a −36·8 g decrease in newborn weight per 0·62 mmol/l (or 1 g/dl) of maternal Hb. SF depletion, but not anaemia, was associated with PB. SGA outcome showed a significant association with anaemia, but not a significant relationship with SF depletion. Conclusions: Birth weight and other-related perinatal outcomes are negatively associated with Hb and SF depletion. Prenatal care attendance reduced the risk of negative birth outcomes
Anthropometry · Biology · Birth weight · Environmental health · Gestational age · Low birth weight · Obstetrics · Population · Pregnancy · Prenatal care · Prospective cohort study · Small for gestational age · Child Nutrition and Water Access · Hemoglobinopathies and Related Disorders · Iron Metabolism and Disorders · Medicine · Internal Medicine · Pediatrics
| Citation velocity | historical |
|---|---|
| Highly cited | No |