Flavonoid intake and disability-adjusted life years due to Alzheimer’s and related dementias
A population-based study involving twenty-three developed countries
Bibliographic Data
| ID | 15095092 |
|---|---|
| Authors | Kristopher Beking (Simon Fraser University), Amandio Vieira (0009-0000-1163-2183, Simon Fraser University, corresponding author) |
| Year | 2010 |
| Volume | 13 |
| Issue | 9 |
| Pages | 1403-1409 |
| Publication date | 2010-09-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Public Health Nutrition (JOURNAL) |
| Journal identifiers | ISSN: 1368-9800 • E-ISSN: 1475-2727 |
| Publisher | Cambridge University Press (CUP) (PUBLISHER) |
| DOI | 10.1017/s1368980009992990 |
| PMID | 20059796 |
| OpenAlex | W2154001593 |
| Language | EN |
| Citations received | 1 |
| References cited | 45 |
Objective Dietary flavonoids and their metabolites may have neuroprotective effects against age-associated neurodegenerative disorders such as Alzheimer’s and related dementias (dementia). There is a lack of population studies, however, on correlations between flavonoid intake and dementia. The main objective of the present study was to analyse such a relationship at a large-scale population level. Design Based on global data (FAO, WHO), databases were generated for: (i) flavonoid content of foods; (ii) per capita national dietary intakes of flavonoids and other dietary factors; and (iii) disability-adjusted life years – a measure of burden and death – due to dementia. Five major flavonoid subclasses were examined. To minimize influences due to accuracy and reliability of the disease source data, twenty-three developed countries were selected after statistical evaluation. Results Flavonols and combined flavonoids (all five combined) intakes were the only two parameters with significant ( P Conclusions At a global level, and in the context of different genetic backgrounds, our results suggest that higher consumption of dietary flavonoids, especially flavonols, is associated with lower population rates of dementia in these countries
Antioxidant · Biology · Confounding · Context (archaeology · Dementia · Disease · Environmental health · Flavonoid · Flavonols · Population · Ginkgo biloba and Cashew Applications · Medicine · Neurological Disease Mechanisms and Treatments · Phytochemicals and Antioxidant Activities · Gerontology · Internal Medicine
| Citations per year | 0.17 |
|---|---|
| Citation span | 2020 - 2020 (1) |
| Highly cited | No |