Weight and body composition in a cohort of HIV-positive men and women
Bibliographic Data
| ID | 15095261 |
|---|---|
| Authors | JE Forrester (Tufts University, corresponding author), Donna Spiegelman (0000-0003-4006-4650, Harvard University), M Woods, Margo N Woods (Tufts University), TA Knox, T A Knox (Tufts Medical Center), JM Fauntleroy, SL Gorbach, S L Gorbach (Tufts University) |
| Year | 2001 |
| Volume | 4 |
| Issue | 3 |
| Pages | 743-747 |
| Publication date | 2001-06-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Public Health Nutrition (JOURNAL) |
| Journal identifiers | ISSN: 1368-9800 • E-ISSN: 1475-2727 |
| Publisher | Cambridge University Press (CUP) (PUBLISHER) |
| DOI | 10.1079/phn200099 |
| PMID | 11415480 |
| OpenAlex | W2150427276 |
| Language | EN |
| Citations received | 1 |
| References cited | 18 |
Objective: At issue is whether weight loss in HIV infection is a cachectic process, characterised by loss of lean body mass with conservation of fat, or a process of starvation. We present data on body composition from 516 persons at different stages of HIV infection as determined by CD4 counts. Design: Cross-sectional analyses of body composition in relation to CD4 count. Setting: The baseline data from a prospective cohort study of outcomes in HIV/AIDS in relation to nutritional status in Boston, Massachusetts, USA. Subjects: The first 516 subjects with HIV/AIDS to enrol in the study. Results: Differences in weight in relation to CD4 counts were present only at CD4 counts of 600 or less (slope below CD4=600 : 1.9 kg per 100 CD4 cells, P On average, 68% of the difference in weight over CD4 counts was fat (slope: 1.3 kg fat per 100 CD4 cells, P ). Conclusions: This cross-sectional analysis suggests that weight loss consists principally of fat loss in those persons with adequate fat stores. This observation will need to be confirmed in longitudinal analyses
Body weight · Cohort · Cohort study · Composition (language · Human immunodeficiency virus (HIV · Lean body mass · Obesity · Prospective cohort study · Weight loss · Demography · Diet and metabolism studies · HIV-related health complications and treatments · Medicine · Nutrition and Health in Aging · Gerontology · Immunology · Internal Medicine · Physiology
| Citations per year | 0.06 |
|---|---|
| Citation span | 2010 - 2010 (1) |
| Highly cited | No |