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Assessment of exposure to methylmercury in pregnant Japanese women by FFQ

Bibliographic Data

ID15095428
AuthorsKozue Yaginuma-Sakurai (Tohoku University, corresponding author), Miyuki Shimada (Tohoku University), Takashi Ohba (Tohoku University), Kunihiko Nakai (0000-0001-8468-4056, Tohoku University), Keita Suzuki (0000-0003-1762-2116, Tohoku University), Naoyuki Kurokawa (Tohoku University), Satomi Kameo (Tohoku University), HIROSHI SATOH (0000-0003-4618-8873, Tohoku University)
Year2009
Volume12
Issue12
Pages2352-2358
Publication date2009-12-01
Open AccessYes
TypeARTICLE
VenuePublic Health Nutrition (JOURNAL)
Journal identifiersISSN: 1368-9800 • E-ISSN: 1475-2727
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1368980009005011
PMID19344539
OpenAlexW2116592267
LanguageEN
Citations received3
References cited23

Objective To examine whether an FFQ can be used for assessing exposure to methylmercury (MeHg) by estimating MeHg intake from seafood consumption using the FFQ and confirming the accuracy of the estimated value. Design Seafood consumption of pregnant women was assessed using the FFQ. Total mercury (T-Hg) concentrations of maternal red blood cells (RBC) and hair were measured as exposure indices of MeHg. Setting A prospective birth cohort study, the Tohoku Study of Child Development (TSCD), which has been ongoing since 2001. Subjects The subjects were 609 pregnant Japanese women who were enrolled in the TSCD. Results MeHg intake was estimated from seafood consumption determined using the FFQ and the MeHg concentrations in each type of seafood. The accuracy of the estimated value was confirmed by comparison with T-Hg in RBC and hair. Estimated MeHg intake was 42·3 μg/week, and 43·0 % of that was from large predatory fish. Compared with the Japanese tolerable weekly intake, in total 12·5 % of the subjects exceeded it. T-Hg concentrations in RBC and hair were significantly correlated with estimated MeHg intake: r = 0·325 ( P r = 0·305 ( P Conclusions Estimated MeHg intake based on the FFQ was significantly associated with T-Hg concentrations in RBC and hair. Although the estimated value involves uncertainties, the FFQ appears to be a useful tool for assessment of exposure to MeHg

Animal science · Bioaccumulation · Biology · Fish · Fish consumption · Fishery · Mercury (programming language · Methylmercury · Prospective cohort study · Air Quality and Health Impacts · Chemistry · Heavy Metal Exposure and Toxicity · Medicine · Mercury impact and mitigation studies · Environmental Chemistry · Internal Medicine · Physiology

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Citations per year0.25
Citation span2014 - 2021 (8)
Highly citedNo

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