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Bisphenol A exposure and associations with obesity among adults

A critical review

Bibliographic Data

ID15095454
AuthorsSarah J Oppeneer (Georgetown University), Kim Robien (0000-0002-2120-2280, Milken Institute)
Year2015
Volume18
Issue10
Pages1847-1863
Publication date2015-07-01
Open AccessYes
TypeARTICLE
VenuePublic Health Nutrition (JOURNAL)
Journal identifiersISSN: 1368-9800 • E-ISSN: 1475-2727
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1368980014002213
PMID25311796
OpenAlexW2127123470
LanguageEN
References cited95

Objective To review the literature on bisphenol A (BPA) exposure and obesity in human populations. Design Systematic review of the literature via searches of PubMed, EMBASE, Web of Science and reference lists for articles published to 1 August 2014. Setting China, Italy, Japan, Republic of Korea, Sweden, UK, USA. Subjects Adults (≥18 years). Results Eighteen articles were identified and included in the review. Twelve studies included secondary evaluations of BPA exposure and BMI, and six studies evaluated body composition as the primary outcome. All analyses were cross-sectional and no study included in the review received a positive quality rating (twelve negative, six neutral). Eight studies observed a statistically significant positive association between urinary or serum BPA levels and BMI, and ten studies observed no association. Studies where BMI was a primary outcome and studies of neutral quality were more likely to observe an association. Conclusions Study results are conflicting and significant methodological issues limit the ability to draw conclusions from these studies. Prospective studies that measure BPA exposure and changes in body weight and composition are needed to establish temporality, causality and the direction of any observed associations

Body mass index · Environmental health · Obesity · Demography · Effects and risks of endocrine disrupting chemicals · Health, Environment, Cognitive Aging · Medicine · Psychology · Skin Protection and Aging · Gerontology · Internal Medicine

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