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Impact of nutritional and multiple micronutrients supplementation to lactating mothers 6 months postpartum on the maternal and infant micronutrient status

A randomised controlled trial in Delhi, India

Bibliographic Data

ID15096431
AuthorsRukman Manapurath (0000-0003-2022-8742, Society for Applied Studies), Ranadip Chowdhury (0000-0002-0055-6653, Society for Applied Studies), Ravi Prakash Upadhyay (0000-0003-0767-9637, Society for Applied Studies), Beena Bose (0000-0001-6705-8803, St John’s Medical College), Sarita Devi (0000-0002-8344-6897, St John’s Medical College), Pratibha Dwarkanath (0000-0002-9843-1057, St John’s Medical College), Anura V Kurpad (0000-0001-7998-2438, St John’s Medical College), Neeraj Bhandari (0000-0003-0349-087X, Society for Applied Studies), Nita Bhandari (Society for Applied Studies), Sunita Taneja (0000-0003-3338-9799, Society for Applied Studies, corresponding author)
Year2024
Volume27
Issue1
Publication date2024-01-01
Open AccessYes
TypeARTICLE
VenuePublic Health Nutrition (JOURNAL)
Journal identifiersISSN: 1368-9800 • E-ISSN: 1475-2727
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s1368980024001824
OpenAlexW4402854113
LanguageEN
Citations received1
References cited34

Objectives: To assess the impact of nutritional and multiple-micronutrient supplementation to lactating mothers on the micronutrient status of mother–infant dyad at 6 months of age postnatally. Design: This study was a trial that aimed to investigate the impact of maternal nutritional supplementation on infant growth. A secondary objective was to assess the effect on the micronutrient status of mother–infant pairs. The intervention group mothers received snacks with 600 kcal energy, 20 g protein and daily micronutrient tablets. Setting: Blood samples were collected from both mothers and infants at 6 months. Participants: The participants in this study were mother–infant pairs. The micronutrient status of these pairs was assessed through blood samples, focusing on vitamins A, D, B 12 , ferritin, Zn and folate. Results: Micronutrient analysis of serum samples from 600 mother–infant pairs showed that mothers in the intervention group had higher levels of serum ferritin (mean difference (MD) 14·7 ng/ml), retinol (MD 0·6 μmol/l), folate (MD 3·3 ng/ml) and vitamin D (1·03 ng/ml) at 6 months postpartum. Additionally, the supplementation was associated with a higher mean ± sd of serum ferritin (MD 8·9 ng/ml) and vitamin A (MD 0·2 μmol/l) levels in infants at 6 months. Conclusions: The study found that supplementing maternal nutrition with additional dietary and micronutrient intakes during lactation improved maternal micronutrient status and slightly increased ferritin and vitamin A levels in infants at 6 months. The findings highlight the importance of nutritional interventions for improving the micronutrient health of mother–infant pairs, with significant public health implications. Trial registered at www.clinicaltrials.gov (CTRI/2018/04/013095)

Breastfeeding · Environmental health · Ferritin · Malnutrition · Micronutrient · Micronutrient deficiency · Vitamin · Child Nutrition and Water Access · Iron Metabolism and Disorders · Medicine · Nutritional Studies and Diet · Endocrinology · Internal Medicine · Pediatrics · Physiology

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Citations per year1
Citation span2026 - 2026 (1)
Highly citedNo

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