Association of fractures with caffeine and alcohol in postmenopausal women
The Iowa Women's Health Study
Bibliographic Data
| ID | 15096811 |
|---|---|
| Authors | Solveig A Hansen (corresponding author), Aaron R Folsom (0000-0003-2635-2699, Minnesota Department of Health), Lawrence H Kushi (0000-0001-9136-1175, University of Minnesota), Thomas A Sellers (0000-0002-7832-0405, Mayo Clinic) |
| Year | 2000 |
| Volume | 3 |
| Issue | 3 |
| Pages | 253-261 |
| Publication date | 2000-09-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Public Health Nutrition (JOURNAL) |
| Journal identifiers | ISSN: 1368-9800 • E-ISSN: 1475-2727 |
| Publisher | Cambridge University Press (CUP) (PUBLISHER) |
| DOI | 10.1017/s136898000000029x |
| PMID | 10979145 |
| OpenAlex | W2089826348 |
| Language | EN |
| Citations received | 1 |
| References cited | 77 |
Objective To assess whether alcoholic and caffeinated beverages are associated with risk of fractures in women. Setting Population-based sample surveyed by post. Subjects A total of 34703 postmenopausal Iowan women aged 55–69 years were surveyed. Design A cohort of women reported alcoholic and caffeinated beverage intake and were followed for 6.5 years for fracture occurrence. Relative risks (RR) and 95% confidence intervals (CI) were computed using Cox proportional hazards regression. Covariates included age, tobacco use, physical activity, body mass index (BMI), waist to hip ratio (WHR), oestrogen use and calcium intake. Results At least one fracture was reported by 4378 women (389 upper arm, 288 forearm, 1128 wrist, 275 hip, 416 vertebral and 2920 other fractures). The adjusted RR for highest versus lowest caffeine intake quintiles was 1.09 (95% CI 0.99–1.21) for combined fracture sites. Wrist fractures were associated positively (RR for extreme quintiles 1.37, 95% CI 1.11–1.69) and upper arm fractures were negatively associated (RR 0.67, 95% CI 0.48–0.94) with caffeine intake. The age-adjusted RR of total fractures for highest versus lowest frequency of beer usage was 1.55 (95% CI 1.25–1.92) and for liquor was 1.25 (95% CI 1.03–1.54). No other association was found between any specific fracture site and alcohol intake. Conclusions We found a modest increase in fracture risk associated with highest caffeine intake, varying by site. Alcohol intake was low, but it also showed a weak positive association with fracture risk
Body mass index · Caffeine · Cohort · Cohort study · Confidence interval · Environmental health · Hip fracture · Osteoporosis · Population · Relative risk · Bone health and osteoporosis research · Demography · Medicine · Nutrition and Health in Aging · Nutritional Studies and Diet · Internal Medicine
Reproducibility and Validity of a Semiquantitative Food Frequency Questionnaire
Fracture rates calculated from fracture histories in normal postmenopausal women
Race and sex differences in hip fracture incidence
Self-report and medical record report agreement of selected medical conditions in the elderly
| Citations per year | 0.04 |
|---|---|
| Citation span | 2002 - 2002 (1) |
| Highly cited | No |