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Prevalence of ocular signs and subclinical vitamin A deficiency and its determinants among rural pre-school children in India

Bibliographic Data

ID15096852
AuthorsAvula Laxmaiah (0000-0002-7799-271X, National Institute of Nutrition, corresponding author), Madhavan K Nair (National Institute of Nutrition), N Arlappa (0000-0001-5405-1872, Indian Council of Medical Research), Raghu Pullakhandam (0000-0002-3758-667X, Indian Council of Medical Research), Pullakhandam Raghu, N Balakrishna (0000-0002-5613-0942, Indian Council of Medical Research), Kodavanti Mallikharjuna Rao (National Institute of Nutrition), Chitty Galreddy (Indian Council of Medical Research), Sharad Kumar (0000-0001-7126-9814), Sharad Kumar Suthar (0000-0003-3609-8057, Indian Council of Medical Research), Manachala Ravindranath (National Institute of Nutrition), Varaganti Vikas Rao (National Institute of Nutrition), G N V Brahmam (National Institute of Nutrition), Ginnela NV Brahmam
Year2012
Volume15
Issue4
Pages568-577
Publication date2012-04-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePublic Health Nutrition (JOURNAL)
Journal identifiersISSN: 1368-9800 • E-ISSN: 1475-2727
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s136898001100214x
PMID21884647
OpenAlexW2160759759
LanguageEN
Citations received5
References cited28

Objective To assess the magnitude and determinants of vitamin A deficiency (VAD) and coverage of vitamin A supplementation (VAS) among pre-school children. Design A community-based cross-sectional study was carried out by adopting a multistage, stratified, random sampling procedure. Setting Rural areas of eight states in India. Subjects Pre-school children and their mothers were covered. Results A total of 71 591 pre-school children were clinically examined for ocular signs of VAD. Serum retinol concentrations in dried blood spots were assessed in a sub-sample of 3954 children using HPLC. The prevalence of Bitot spots was 0·8 %. The total ocular signs were significantly higher ( P P Conclusions The study revealed that VAD is a major nutritional problem and coverage of VAS was poor. The important determinants of VAD were illiteracy, low socio-economic status, occupation and poor sanitation. Strengthening the existing VAS programme and focused attention on dietary diversification are essential for prevention of VAD

Anthropometry · Cross-sectional study · Odds ratio · Retinol · Subclinical infection · Vitamin · Vitamin A deficiency · Antioxidant Activity and Oxidative Stress · Demography · Medicine · Retinoids in leukemia and cellular processes · Vitamin C and Antioxidants Research · Internal Medicine · Pediatrics

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Unique citing works5
Citations per year0,45
Citation span2015 - 2023 (9)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 5

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