The WHO recommendation of home fortification of foods with multiple-micronutrient powders in children under 2 years of age and its effectiveness on anaemia and weight
A pragmatic cluster-randomized controlled trial
Bibliographic Data
| ID | 15097102 |
|---|---|
| Authors | Yassinmè Elysée Somassè (Université Libre de Bruxelles, corresponding author), Michèle Dramaix (Université Libre de Bruxelles), Boncana Traoré (Mali-Folkecenter), Ildephonse Ngabonziza (Université Libre de Bruxelles), Oussouby Touré (0000-0002-9928-102X, Institut National de Recherche en Santé Publique), Ousmane Touré, Mamadou Konaté (Mali-Folkecenter), Mamadou Diallo (0000-0002-0376-3631, Mali-Folkecenter), Philippe Donnen (Université Libre de Bruxelles) |
| Year | 2018 |
| Volume | 21 |
| Issue | 7 |
| Pages | 1350-1358 |
| Publication date | 2018-05-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Public Health Nutrition (JOURNAL) |
| Journal identifiers | ISSN: 1368-9800 • E-ISSN: 1475-2727 |
| Publisher | Cambridge University Press (CUP) (PUBLISHER) |
| DOI | 10.1017/s1368980017003858 |
| PMID | 29352829 |
| OpenAlex | W2791993196 |
| Language | EN |
| Citations received | 1 |
| References cited | 30 |
Objective To assess under real community settings the effectiveness of the WHO strategy of home fortification of foods (HFF) with multiple-micronutrient powders on Hb change, anaemia and weight in children. Design A pragmatic cluster-randomized controlled trial. Setting Forty villages in the Nioro Circle in Mali and 722 children aged 6–23 months were randomized to the intervention or control group. The intervention consisted of a daily dose of multiple-micronutrient powder for 3 months; in the control group, no supplement was given. In both groups, mothers received group education on child complementary feeding. Changes in weight, Hb concentration and anaemia were assessed as primary outcomes at baseline and 3 months. The HFF effect was determined using regression analyses and quantile regression with standard errors taking account of the cluster design. Subjects Children aged 6–23 months. Results Overall prevalence of anaemia in the sample was high: 90 %. HFF provided a modest but statistically significant Hb change v . no intervention (0·50 v . 0·09 g/dl, P =0·023). Prevalence of anaemia changed little: 91·3–85·8 % ( P =0·04) in the intervention group v . 88·1–87·5 % % ( P =0·86) in the control group. Proportion of severe anaemia was reduced by 84 % (from 9·8 to 1·6 %) in the intervention group, but increased in the control group (from 8·5 to 10·8 %). No effect was observed on weight. Conclusions The WHO HFF strategy to fight anaemia showed a modest change on Hb concentration and significantly reduced the rate of severe anaemia
Anemia · Cluster (spacecraft · Cluster randomised controlled trial · Food fortification · Fortification · Intervention (counseling · Micronutrient · Randomized controlled trial · Child Nutrition and Water Access · Food Security and Health in Diverse Populations · Iron Metabolism and Disorders · Medicine · Food Science · Internal Medicine · Pediatrics
Impact of maternal education about complementary feeding and provision of complementary foods on child growth in developing countries
The Epidemiology of Global Micronutrient Deficiencies
Anaemia in low-income and middle-income countries
In‐home fortification with 2.5 mg iron as NaFeEdta does not reduce anaemia but increases weight gain
Effectiveness of Micronutrient Powders (MNP) in women and children
| Unique citing works | 1 |
|---|---|
| Citations per year | 1 |
| Citation span | 2025 - 2025 (1) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 1 |