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Association between dietary sodium intake and non-alcoholic fatty liver disease in the US population

Bibliographic Data

ID15097240
AuthorsLong Zhou (0000-0003-3379-9771, Xi'an Jiaotong University), Yuxuan Yang (0009-0000-5292-713X, Xi'an Jiaotong University), Yang Feng (0000-0002-9453-5924, Xi'an Jiaotong University), Xiaodan Zhao (Xi'an Jiaotong University), Yameng Fan (0009-0001-3724-5218, Xi'an Jiaotong University), Jie Rong (0009-0006-9079-7915, Xi'an Jiaotong University), Liancheng Zhao (0000-0002-9060-8102, Chinese Academy of Medical Sciences & Peking Union Medical College), Yan Yu (0000-0003-4031-252X, Xi'an Jiaotong University, corresponding author)
Year2021
Volume24
Issue5
Pages993-1000
Publication date2021-04-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePublic Health Nutrition (JOURNAL)
Journal identifiersISSN: 1368-9800 • E-ISSN: 1475-2727
PublisherCambridge University Press (CUP) (PUBLISHER)
DOI10.1017/s136898001900483x
PMID32312347
OpenAlexW3016704197
LanguageEN
Citations received1
References cited23

Objective: To explore the association between dietary Na intake and non-alcoholic fatty liver disease (NAFLD) in a nationally representative sample of the US population. Design: In this cross-sectional study, the associations between Na intake and NAFLD, defined by the hepatic steatosis index (HSI) and the fatty liver index (FLI), were assessed through multivariable logistic regression models. Setting: Communities in the USA from 2007 to 2014. Participants: Men and women aged 20 years and older. Results: A total of 11 022 participants were included in the HSI-defined NAFLD analysis, and a subsample of 5320 participants was included in the FLI-defined NAFLD analysis. Compared with the lowest quartile of Na intake, the highest quartile had a multivariate-adjusted OR and 95 % CI of 1·46 (1·29, 1·65) for NAFLD as defined by HSI, and 1·41 (1·18, 1·69) for NAFLD as defined by FLI. This association was, to some degree, attenuated but remained significant after adjusting for several related metabolic parameters, including BMI, hypertension, hypercholesterolaemia, and diabetes. Conclusions: Findings from the current study indicate that dietary Na intake is positively associated with NAFLD in US adults

Alcohol · Alcohol intake · Alcoholic liver disease · Biology · Cirrhosis · Disease · Environmental health · Fatty liver · Population · Diet, Metabolism, and Disease · Liver Disease Diagnosis and Treatment · Medicine · Sodium Intake and Health · Biochemistry · Gastroenterology · Internal Medicine · Physiology

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    Open Access•Yameng Fan, Yinyin Zhang et al.•BMC Public Health•2021

  • Salt intake, stroke, and cardiovascular disease

    Open Access•P Strazzullo, L D'Elia et al.•BMJ•2009

Unique citing works1
Citations per year0,2
Citation span2021 - 2021 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1

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Open DOISci-HubOpen Access
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