Inverse relationship between vitamin D status and insulin resistance and the risk of impaired fasting glucose in Korean children and adolescents
The Korean National Health and Nutrition Examination Survey (KNHANES) 2009–2010
Bibliographic Data
| ID | 15097330 |
|---|---|
| Authors | Seung Joon Chung (Seoul National University Hospital), Young Ah Lee (0000-0002-0414-842X, Seoul National University Hospital, corresponding author), Hyunsook Hong (0000-0003-0955-4176, Seoul National University Hospital), Min Jae Kang (0000-0003-3080-0941, Seoul National University Hospital), Hyun Jin Kwon (0000-0003-1187-737X, Korea National Sport University), Choong Ho Shin (0000-0002-9813-1134, Seoul National University Hospital), Sei Won Yang (0000-0002-5304-5750, Seoul National University Hospital) |
| Year | 2014 |
| Volume | 17 |
| Issue | 4 |
| Pages | 795-802 |
| Publication date | 2014-04-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Public Health Nutrition (JOURNAL) |
| Journal identifiers | ISSN: 1368-9800 • E-ISSN: 1475-2727 |
| Publisher | Cambridge University Press (CUP) (PUBLISHER) |
| DOI | 10.1017/s1368980013002334 |
| PMID | 24050711 |
| OpenAlex | W1991817371 |
| Language | EN |
| Citations received | 2 |
| References cited | 28 |
Objective To investigate whether low vitamin D status was related to insulin resistance (IR) or impaired fasting glucose (IFG) in Korean adolescents, after adjusting for total body fat mass (FM). Design A cross-sectional study. Setting Korea National Health and Nutrition Examination Survey (KNAHNES) 2009–2010. Subjects In total, 1466 participants (769 males) aged 10–19 years were assessed for serum 25-hydroxyvitamin D (25(OH)D) levels, for FM by whole-body dual-energy X-ray absorptiometry and for IR by homeostasis model assessment (HOMA-IR) after an 8 h fast. Results Age-, sex-, season- and physical-activity-adjusted regression models showed that serum 25(OH)D levels were significantly related to markers of adiposity ( P = 0·016 for FM (g), P = 0·023 for FM (%) and P = 0·035 for fat mass index). When the participants were stratified into three 25(OH)D categories ( n 553), 37·5 to n 543) and ≥ 50 nmol/l ( n 370)), significantly decreasing trends were observed for fasting insulin (all P P P for trend P Conclusions There was a significant inverse relationship between vitamin D status and IR and the risk of IFG, independent of adiposity, in Korean adolescents
Body mass index · Environmental health · Impaired fasting glucose · Impaired glucose tolerance · Insulin · Insulin resistance · Logistic regression · National Health and Nutrition Examination Survey · Odds ratio · Population · Vitamin D and neurology · vitamin D deficiency · Demography · Diet and metabolism studies · Medicine · Nutritional Studies and Diet · Vitamin D Research Studies · Endocrinology · Internal Medicine
| Citations per year | 0.17 |
|---|---|
| Citation span | 2014 - 2019 (6) |
| Highly cited | No |