Relationship of serum carotenoids and retinol with anaemia among pre-school children in the northern mountainous region of Vietnam
Bibliographic Data
| ID | 15097362 |
|---|---|
| Authors | Nguyen Cong Khan (VNU University of Science, corresponding author), Phan Van Huan (National Institute of Nutrition), Nguyen Van Nhien (National Institute of Nutrition), Le Danh Tuyen (National Institute of Nutrition), Saskia de Pee (0000-0002-0138-7118), Richard D Semba (0000-0002-8350-2908, Johns Hopkins University) |
| Year | 2010 |
| Volume | 13 |
| Issue | 11 |
| Pages | 1863-1869 |
| Publication date | 2010-11-01 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Public Health Nutrition (JOURNAL) |
| Journal identifiers | ISSN: 1368-9800 • E-ISSN: 1475-2727 |
| Publisher | Cambridge University Press (CUP) (PUBLISHER) |
| DOI | 10.1017/s1368980010000571 |
| PMID | 20587114 |
| OpenAlex | W2146146062 |
| Language | EN |
| Citations received | 1 |
| References cited | 17 |
Objective To characterize the relationship between serum carotenoids, retinol and anaemia among pre-school children. Design A cross-sectional study was conducted in two groups: anaemic and non-anaemic. Serum levels of retinol, α-carotene, β-carotene, β-cryptoxanthin, lycopene, lutein and zeaxanthin were measured in the study subjects. Setting Six rural communes of Dinh Hoa, a rural and mountainous district in Thai Nguyen Province, in the northern mountainous region of Vietnam. Subjects A total of 682 pre-school children, aged 12–72 months, were recruited. Results Geometric mean serum concentrations of carotenoids (μmol/l) were 0·056 for α-carotene, 0·161 for β-carotene, 0·145 for β-cryptoxanthin, 0·078 for lycopene, 0·388 for lutein and 0·075 for zeaxanthin. The mean levels of Hb and serum retinol were 108·8 g/l and 1·02 μmol/l, respectively. The prevalence of anaemia and vitamin A deficiency was 53·7 % and 7·8 %, respectively. After adjusting for sex and stunting, serum retinol concentrations (μmol/l; OR = 2·06, 95 % CI 1·10, 3·86, P = 0·024) and total provitamin A carotenoids (μmol/l; OR = 1·52, 95 % CI 1·01, 2·28, P = 0·046) were independently associated with anaemia, but non-provitamin A carotenoids (μmol/l; OR = 0·93, 95 % CI 0·63, 1·37, P = 0·710) were not associated with anaemia. Conclusions Among pre-school children in the northern mountainous region of Vietnam, the prevalences of vitamin A deficiency and anaemia are high, and serum retinol and provitamin A carotenoids are independently associated with anaemia. Further studies are needed to determine if increased consumption of provitamin A carotenoids will reduce anaemia among pre-school children
Biology · Carotenoid · Environmental health · Geography · Retinol · Vitamin · Vitamin A deficiency · Child Nutrition and Water Access · Global Maternal and Child Health · Medicine · Poverty, Education, and Child Welfare · Food Science · Internal Medicine
| Citations per year | 0.5 |
|---|---|
| Citation span | 2024 - 2024 (1) |
| Highly cited | No |