I feel empowered”

Women’s perspectives on and experiences with long-acting injectable antiretroviral therapy in the USA and Spain

Bibliographic Data

ID15098161
AuthorsAndrea Mantsios (0000-0002-3314-9173, Department of Sociology, American University, Washington, DC, USA, corresponding author), Miranda Murray (0009-0000-6870-0941, Department of Sociology, American University, Washington, DC, USA), Tahilin Sanchez Karver (0000-0001-7362-9377, Johns Hopkins University), Wendy Davis (0000-0003-4521-0688, Department of Sociology, American University, Washington, DC, USA), David Margolis (ViiV Healthcare, Raleigh-Durham, Research Triangle Park, NC, USA), David M Margolis (0000-0001-5714-0002, Triangle), Princy Kumar (0000-0002-5994-2727, Georgetown University), Susan Swindells (0000-0001-5826-6037, University of Nebraska Medical Center), U Fritz Bredeek (Metropolis Medical, San Francisco, CA, USA), Miguel García Deltoro (0000-0002-5969-1059, Infectious Disease Service, Consorcio Hospital General Universitario de Valencia, Valencia, Spain), Rafael Rubio (0000-0001-8132-4303, Hospital Universitario 12 De Octubre), Rafael Rubio García (HIV Unit, Hospital Universitario 12 de Octubre, Madrid, Spain), Antonio Antela (0000-0002-4819-0953, Infectious Diseases Unit, Complejo Hospitalario Universitario, Santiago de Compostela, Compostela, Spain), Cindy Garris (0000-0002-2685-1204, ViiV Healthcare, Raleigh-Durham, Research Triangle Park, NC, USA), Mark S Shaefer (0000-0002-0545-7304, Triangle), Mark Shaefer (ViiV Healthcare, Raleigh-Durham, Research Triangle Park, NC, USA), Santiago Cenoz Gomis (ViiV Healthcare, Tres Cantos, Madrid, Spain), Miguel Pascual Bernáldez (ViiV Healthcare, Tres Cantos, Madrid, Spain), Deanna Kerrigan (0000-0001-7401-9159, Department of Sociology, American University, Washington, DC, USA)
Year2021
Volume23
Issue8
Pages1066-1078
Publication date2021-08-02
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueCulture Health & Sexuality (JOURNAL)
Journal identifiersISSN: 1369-1058 • E-ISSN: 1464-5351
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/13691058.2020.1752397
PMID32436478
OpenAlexW3026464856
LanguageEN
Citations received4
References cited22

Long-acting injectable antiretroviral therapy has been shown to be non-inferior to daily oral antiretroviral therapy in clinical trials and may soon become part of clinical care. While most trial participants to date have been men, approximately one quarter of ongoing Phase 3 trial participants are women offering an important opportunity to understand how long-acting antiretroviral therapy is perceived and experienced by women. We conducted in-depth interviews with 80 people living with HIV participating in Phase 2 and 3 clinical trials of long-acting antiretroviral therapy in the USA and Spain. Fifteen percent (12/80) of trial participants interviewed were women. Interviews were audio-recorded, transcribed and coded using content analysis, focused on gender-specific themes. Women shared many of the positive perceptions expressed by men but also had unique perspectives, including finding that long-acting antiretroviral therapy addressed the challenge of remembering pills amidst busy day-to-day realities including multiple roles and responsibilities, is less time consuming and creates less stress compared to oral antiretroviral therapy, and is emotionally freeing and empowering. The gendered nature of women's lives shaped why and how they were satisfied with long-acting antiretroviral therapy. Findings can inform interventions and support systems to facilitate uptake of and adherence to long-acting antiretroviral therapy in women

Alternative medicine · Antiretroviral therapy · Clinical trial · Family medicine · Human immunodeficiency virus (HIV · Pill · Psychiatry · Psychological intervention · Viral load · Adolescent Sexual and Reproductive Health · HIV/AIDS Research and Interventions · LGBTQ Health, Identity, and Policy · Medicine · Nursing · Internal Medicine

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