Curcumin and vitamin E improve hot flashes, lipid profile, and fasting blood glucose without any detrimental effect on the liver and renal function in postmenopausal women
A triple-blind placebo-controlled clinical trial
Bibliographic Data
We conducted this study to evaluate the efficacy of Curcumin and vitamin E on hot flashes, lipid profile, blood glucose, and hepatic & renal biomarkers. Eighty-four postmenopausal women were randomly assigned into three groups to receive one Curcumin 500 milligram, vitamin E 200 IU, or placebo capsules twice/daily/eight weeks. In comparison with placebo, vitamin E significantly decreased the number of hot flashes (P = 0.002), serum triglyceride (P < 0.001), and aspartate aminotransferase (P = 0.007), while it increased high-density lipoprotein cholesterol (P = 0.005). Curcumin decreased significantly fasting blood glucose (P = 0.007), total cholesterol (P = 0.015), and triglyceride (P = 0.007) compared to placebo. We conclude that vitamin E reduced the incidence of hot flashes by nearly one-third of the base amount. It improved serum lipid profile and aspartate aminotransferase. Curcumin ameliorated fasting blood glucose and serum lipid profile
Antioxidant · Blood lipids · Cholesterol · Curcumin · Lipid Profile · Liver function · Placebo · Triglyceride · Vitamin · Vitamin C · Vitamin E · Antioxidant Activity and Oxidative Stress · Chemistry · Curcumin's Biomedical Applications · Medicine · Retinoids in leukemia and cellular processes · Biochemistry · Endocrinology · Internal Medicine · Pharmacology
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