Impact of Covid-19 on Clinical Research and Inclusion of Diverse Populations
Bibliographic Data
| ID | 15315112 |
|---|---|
| Authors | Daniel T Lackland (0000-0001-5733-6283, Medical University of South Carolina, corresponding author), Catrina Sims‐Robinson (0000-0003-4776-5839, Medical University of South Carolina), Joy Buie (0000-0003-4026-4812, Medical University of South Carolina), Joy N Jones Buie, Jenifer H Voeks (0000-0002-5544-3322, Medical University of South Carolina) |
| Year | 2020 |
| Volume | 30 |
| Issue | 3 |
| Pages | 429-432 |
| Publication date | 2020-07-08 |
| Open Access | No |
| Type | ARTICLE |
| Venue | Ethnicity & Disease (JOURNAL) |
| Journal identifiers | ISSN: 1049-510X • E-ISSN: 1945-0826 |
| Publisher | Ethnicity & Disease, Inc (PUBLISHER) |
| DOI | 10.18865/ed.30.3.429 |
| PMID | 32742146 |
| OpenAlex | W3041457259 |
| Language | EN |
| Citations received | 5 |
| References cited | 1 |
The randomized clinical trial (RCT) has long been recognized as the 'gold standard' for developing evidence for clinical treatments and vaccines; however, the successful implementation and translation of these findings is predicated upon external validity. The generalization of RCT findings are jeopardized by the lack of participation of at-risk groups such as African Americans, with long-recognized disproportional representation. Distinct factors that deter participation in RCTs include distrust, access, recruitment strategies, perceptions of research, and socioeconomic factors. While strategies have been implemented to improve external validity with greater participation among all segments of the population in RCTs, the coronavirus disease 2019 (COVID-19) pandemic may exacerbate disparities in RCT participation with the potential impact of delaying treatment development and vaccine interventions that are applicable and generalizable. Thus, it is essential to include diverse populations in such strategies and RCTs. This Perspective aims to direct attention to the additional harm from the pandemic as well as a refocus on the unresolved lack of inclusion of diverse populations in conducting RCTs
Coronavirus disease 2019 (COVID-19 · Disease · Distrust · Environmental health · Family medicine · Gold standard (test · Harm · Inclusion (mineral · Pandemic · Population · Psychiatry · Psychological intervention · Psychotherapist · Randomized controlled trial · Ethics in Clinical Research · Health Systems, Economic Evaluations, Quality of Life · Medicine · Psychology · Social Psychology · Vaccine Coverage and Hesitancy · Internal Medicine
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Promoting the Participation of “Hard-to-Reach” Migrant Populations in Qualitative Public Health Research during the Covid-19 Pandemic in Chile
Establishing a Community Engagement Consultative Resource
| Citations per year | 0.83 |
|---|---|
| Citation span | 2020 - 2024 (5) |
| Highly cited | No |