Efficacy is Not Everything

Eliciting Women’s Preferences for a Vaginal HIV Prevention Product Using a Discrete-Choice Experiment

Datos Bibliográficos

ID15334737
AutoresErica N Browne (0000-0003-2069-6589, RTI International, autor de correspondencia), Elizabeth Montgomery (0000-0002-5477-4445, RTI International), Carol Mansfield (0000-0002-3144-8938, RTI International), Marco Boeri (0000-0001-7346-2132, RTI International), Brennan Mange (RTI International), Mags Beksinska (0000-0002-4169-4112, University of the Witwatersrand), Jill L Schwartz (Eastern Virginia Medical School), Meredith R Clark (0000-0002-4476-8287, Eastern Virginia Medical School), Gustavo F Doncel (0009-0009-9641-1325, Eastern Virginia Medical School), Jenni Smit (University of the Witwatersrand), Zvavahera M Chirenje (0000-0003-3538-5150, University of Zimbabwe), Ariane Van Der Straten (0000-0001-8536-648X, RTI International)
Año2019
Volumen24
Número5
Páginas1443-1451
Fecha de publicación2019-11-06
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaAIDS and Behavior (JOURNAL)
Identificadores de la revistaISSN: 1090-7165 • E-ISSN: 1573-3254
EditorialSpringer Science+Business Media (PUBLISHER • DE)
DOI10.1007/s10461-019-02715-1
PMID31696371
OpenAlexW2983622305
IdiomaEN
Citas recibidas9
Referencias citadas33

As new female-initiated HIV prevention products enter development, it is crucial to incorporate women's preferences to ensure products will be desired, accepted, and used. A discrete-choice experiment was designed to assess the relative importance of six attributes to stated choice of a vaginally delivered HIV prevention product. Sexually active women in South Africa and Zimbabwe aged 18-30 were recruited from two samples: product-experienced women from a randomized trial of four vaginal placebo forms and product-naïve community members. In a tablet-administered survey, 395 women chose between two hypothetical products over eight choice sets. Efficacy was the most important, but there were identifiable preferences among other attributes. Women preferred a product that also prevented pregnancy and caused some wetness (p < 0.001). They disliked a daily-use product (p = 0.002) and insertion by finger (p = 0.002). Although efficacy drove preference, wetness, pregnancy prevention, and dosing regimen were influential to stated choice of a product, and women were willing to trade some level of efficacy to have other more desired attributes

Alternative medicine · Biology · Economics · Environmental health · Gynecology · Health psychology · Health services · Mate choice · Microbicides for sexually transmitted diseases · Placebo · Population · Preference · Product (mathematics · Public health · Adolescent Sexual and Reproductive Health · Demography · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Nursing · Psychology