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Accuracy and Acceptability of Oral Fluid HIV Self-Testing in a General Adult Population in Kenya

Dados Bibliográficos

ID15337633
AutoresAnn Kurth (0000-0003-2300-6723, autor correspondente), Ann E Kurth, Charles M Cleland (0000-0002-6931-9904, New York University), Nok Chhun (0000-0001-5998-3839, New York University), John E Sidle (Indiana University – Purdue University Indianapolis), Edwin Were (0000-0002-4783-0795, Moi University), Violet Naanyu (0000-0003-0182-1719, AMPATH), Wilfred Emonyi (0000-0001-8027-0585, AMPATH), Stephen Macharia (Moi University), Stephen M Macharia, Edwin Sang (AMPATH), Abraham Siika (0000-0001-7669-6612, Moi University), Abraham M Siika
Ano2015
Volume20
Fascículo4
Páginas870-879
Data de publicação2015-10-05
Peer ReviewedSim
Open AccessSim
TipoARTICLE
PeriódicoAIDS and Behavior (JOURNAL)
Identificadores do periódicoISSN: 1090-7165 • E-ISSN: 1573-3254
EditoraSpringer Science+Business Media (PUBLISHER • DE)
DOI10.1007/s10461-015-1213-9
PMID26438487
OpenAlexW1867571570
IdiomaEN
Citações recebidas28
Referências citadas21

We evaluated performance, accuracy, and acceptability parameters of unsupervised oral fluid (OF) HIV self-testing (HIVST) in a general population in western Kenya. In a prospective validation design, we enrolled 240 adults to perform rapid OF HIVST and compared results to staff administered OF and rapid fingerstick tests. All reactive, discrepant, and a proportion of negative results were confirmed with lab ELISA. Twenty participants were video-recorded conducting self-testing. All participants completed a staff administered survey before and after HIVST to assess attitudes towards OF HIVST acceptability. HIV prevalence was 14.6 %. Thirty-six of the 239 HIVSTs were invalid (15.1 %; 95 % CI 11.1-20.1 %), with males twice as likely to have invalid results as females. HIVST sensitivity was 89.7 % (95 % CI 73-98 %) and specificity was 98 % (95 % CI 89-99 %). Although sensitivity was somewhat lower than expected, there is clear interest in, and high acceptability (94 %) of OF HIV self-testing

Environmental health · Family medicine · Fingerstick · Health psychology · Human immunodeficiency virus (HIV · Pathology · Population · Public health · HIV Research and Treatment · HIV/AIDS oral health manifestations · HIV/AIDS Research and Interventions · Medicine · Internal Medicine

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Obras citantes distintas28
Citações por ano2,8
Intervalo de citações2016 - 2025 (10)
Velocidade de citaçãorecent
Altamente citadoNão
Tipos de citaçãoNeutras: 28
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