HIV Stigma and Depressive Symptoms are Related to Adherence and Virological Response to Antiretroviral Treatment Among Immigrant and Indigenous HIV Infected Patients

Datos Bibliográficos

ID15338201
AutoresI Marion Sumari-de Boer (0000-0002-5433-0406, Amsterdam UMC Location University of Amsterdam, autor de correspondencia), Mirjam A G Sprangers (0000-0002-3728-6933, Amsterdam UMC Location University of Amsterdam), Jan M Prins (0000-0002-5415-8933, Amsterdam UMC Location University of Amsterdam), Pythia T Nieuwkerk (0000-0002-2616-1414, Amsterdam UMC Location University of Amsterdam)
Año2011
Volumen16
Número6
Páginas1681-1689
Fecha de publicación2011-12-24
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaAIDS and Behavior (JOURNAL)
Identificadores de la revistaISSN: 1090-7165 • E-ISSN: 1573-3254
EditorialSpringer Science+Business Media (PUBLISHER • DE)
DOI10.1007/s10461-011-0112-y
PMID22198315
PMCIDPMC3401302
OpenAlexW2005385057
IdiomaEN
Citas recibidas35
Referencias citadas56

We compared adherence to cART and virological response between indigenous and immigrant HIV-infected patients in the Netherlands, and investigated if a possible difference was related to a difference in the psychosocial variables: HIV-stigma, quality-of-life, depression and beliefs about medications. Psychosocial variables were assessed using validated questionnaires administered during a face-to-face interview. Adherence was assessed trough pharmacy-refill monitoring. We assessed associations between psychosocial variables and non-adherence and having detectable plasma viral load using logistic regression analyses. Two-hundred-two patients participated of whom 112 (55%) were immigrants. Viral load was detectable in 6% of indigenous patients and in 15% of the immigrants (P < 0.01). In multivariate analyses, higher HIV-stigma and prior virological failure were associated with non-adherence, and depressive symptoms, prior virological failure and non-adherence with detectable viral load. Our findings suggest that HIV-stigma and depressive symptoms may be targets for interventions aimed at improving adherence and virological response among indigenous and immigrant HIV-infected patients

Health psychology · Human immunodeficiency virus (HIV · Logistic regression · Psychiatry · Psychological intervention · Psychosocial · Public health · Stigma (botany · Viral load · Clinical Psychology · HIV-related health complications and treatments · HIV/AIDS drug development and treatment · HIV/AIDS Research and Interventions · Medicine · Immunology · Internal Medicine