Mediation factors of the association between coronary heart disease and physical activity among rural residents
A cross-sectional study
Bibliographic Data
| ID | 15366751 |
|---|---|
| Authors | Guangcui Xu (0000-0002-3040-0879, Xinxiang Medical University, corresponding author), Jiaojiao Ma (0000-0001-8683-7861, Xinxiang Medical University), Yongbin Wang (0000-0001-7854-7020, Xinxiang Medical University), Ying‐Zheng Zhao (0009-0007-6819-3231, Xinxiang Medical University), Yingzheng Zhao, Ting Fan (0000-0001-8286-0896), Ting‐Jun Fan (0000-0002-5155-7015, Xinxiang Medical University), Jiaxin Lv (0000-0001-9152-160X, Xinxiang Medical University), Yingjun Tao (Xian Center for Disease Control and Prevention), Hui Wu (0000-0003-0296-5204, Xinxiang Medical University), Weidong Wu (0000-0002-5591-2221, Xinxiang Medical University) |
| Year | 2025 |
| Volume | 25 |
| Issue | 1 |
| Pages | 1837-1837 |
| Publication date | 2025-05-19 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | BMC Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1471-2458 • E-ISSN: 1471-2458 |
| Publisher | BioMed Central (PUBLISHER • GB) |
| DOI | 10.1186/s12889-025-23060-0 |
| PMID | 40389927 |
| OpenAlex | W4410508182 |
| Language | EN |
| References cited | 38 |
There is evidence that physical and chemical factors and risky lifestyle behaviours are significantly correlated with elevated susceptibility to coronary heart disease (CHD). Nevertheless, the mediation factors of this relationship are little investigated. This article attempts to assess the mediating factors between CHD and physical activity (PA) in rural residents. We conducted a cross-sectional study of 9,004 permanent residents in rural regions of Xinxiang County, Henan Province. The correlation between CHD and PA was evaluated using a logistic regression model, as well as the association between CHD and its associated risk factors. The robustness of the outcomes was evaluated through sensitivity analysis. The mediating factors of the correlation between CHD and PA in rural residents were explored through mediation analysis. The results showed that CHD was associated with PA (0.72, 95%CI:0.56-0.95), and the levels of fasting insulin (FINS), total cholesterol (TC), and blood glucose (GLU) were associated with PA (-0.92, 95%CI: (-1.48, -0.37), 0.08, 95%CI: (0.01, 0.15), -0.17, 95%CI: (-0.28, -0.06)). The levels of FINS, TC and GLU had significant mediating effects on the association of PA with CHD (1.00, 95%CI: (-0.0028, 0.0000), 1.00, 95%CI: (-0.0016, 0.0000), 1.00, 95%CI: (-0.0014, 0.0000)). In rural populations, PA is associated with CHD, possibly mediated by FINS, TC and GLU, rather than relying solely on the direct effects of PA
Association (psychology · Biostatistics · Coronary heart disease · Cross-sectional study · Environmental health · Mediation · Pathology · Physical activity · Physical therapy · Public health · Cardiac Health and Mental Health · Cardiovascular Health and Risk Factors · Health and Lifestyle Studies · Medicine · Epidemiology · Gerontology · Internal Medicine
| Citation velocity | historical |
|---|---|
| Highly cited | No |