Model of genetic and environmental factors associated with type 2 diabetes mellitus in a Chinese Han population

Bibliographic Data

ID15375383
AuthorsZheng Li (0000-0002-7537-2509, Hangzhou Normal University, corresponding author), Chengyin Ye (0000-0001-8384-1857, Hangzhou Normal University), Cheng-Yin Ye, Tianyu Zhao (0000-0001-6265-7372), Tian-Yu Zhao (0000-0002-4424-7959, Shihezi University), Lei Yang (0000-0002-8956-6478, Hangzhou Normal University)
Year2020
Volume20
Issue1
Pages1024-1024
Publication date2020-06-29
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueBMC Public Health (JOURNAL)
Journal identifiersISSN: 1471-2458 • E-ISSN: 1471-2458
PublisherBioMed Central (PUBLISHER • GB)
DOI10.1186/s12889-020-09130-5
PMID32600448
OpenAlexW3039732878
LanguageEN
Citations received1
References cited41

Eventually we identified a set of SNPs and environmental factors: rs5805 in the SLC12A3, rs12654264 in the HMGCR, rs2065412 and rs414936 in the ABCA1, rs96418 in the ZPR1 gene, waistline, degree of education, exercise frequency, hypertension, and the intake of meat. Although there was no interaction between these variables, people with two risk factors had a higher risk of T2DM than those only having one factor. These results provide the theoretical basis for gene and other risk factors screening to prevent T2DM

Biology · Body mass index · Diabetes mellitus · Environmental health · Gene · Genotype · Incidence (geometry · Population · Type 2 diabetes · Type 2 Diabetes Mellitus · Waist · Bioinformatics and Genomic Networks · Genetic Associations and Epidemiology · Medicine · Metabolomics and Mass Spectrometry Studies · Endocrinology · Epidemiology · Gastroenterology · Genetics · Internal Medicine

Tools

Open DOIOpen Access