The progress of mother-to-child transmission of Human Immunodeficiency Virus (HIV) after Dolutegravir (DTG) optimization program
Evidence from a multicenter cohort study in Ethiopia
Bibliographic Data
| ID | 15380983 |
|---|---|
| Authors | Abel Gedefaw (0000-0002-5541-0088, Karolinska University Hospital, corresponding author), Birkneh Tilahun Tadesse (0000-0003-4005-8605, Karolinska University Hospital), Sintayehu Tadesse (Hawassa University), Biruk Kebede (Hawassa University), Siraj Hussen (0000-0002-1193-9377, Hawassa University), Dejene Hailu (Hawassa University), Yifru Berhan (0000-0002-3779-0718, St. Paul's Hospital Millennium Medical College), Eyasu Makonnen (0000-0002-9259-5288, Africa Centres for Disease Control and Prevention), Stefano Vella (0000-0003-2347-5984, Karolinska University Hospital), Eleni Aklillu (0000-0002-9788-0790, Karolinska University Hospital) |
| Year | 2024 |
| Volume | 24 |
| Issue | 1 |
| Pages | 3367-3367 |
| Publication date | 2024-12-03 |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | BMC Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1471-2458 • E-ISSN: 1471-2458 |
| Publisher | BioMed Central (PUBLISHER • GB) |
| DOI | 10.1186/s12889-024-20761-w |
| PMID | 39627710 |
| OpenAlex | W4404974424 |
| Language | EN |
| Citations received | 2 |
| References cited | 25 |
In the studied cohort population, we observed less than 3% MTCT rate at the end of PMTCT care. The findings might suggest the achievement of MTCT elimination at the hospital level. Although the DTG-based regimen demonstrated a lower risk of transmission, other contributing factors, such as late ART initiation, should be urgently addressed. Future research should focus on prospective designs, interventions targeting late ART initiation, and understanding regional disparities to further advance efforts to eliminate MTCT by 2030
Antiretroviral therapy · Breastfeeding · Cohort · Cohort study · Dolutegravir · Environmental health · Human immunodeficiency virus (HIV · Obstetrics · Population · Regimen · Viral load · HIV Research and Treatment · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Immunology · Internal Medicine · Pediatrics
| Citations per year | 2 |
|---|---|
| Citation span | 2026 - 2026 (1) |
| Highly cited | No |