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Second and fourth (2D

(4D) digit ratio in heroin and cannabis addicted patients

Bibliographic Data

ID15415110
AuthorsMehmet Gürkan Gürok (0000-0001-8998-0743, Fırat University, corresponding author), Sevler Yıldız (0000-0002-9951-9093, Botkin Hospital), Dilek Bakış Aksoy (State Hospital), Aslı Kazğan Kılıçaslan (0000-0002-0312-0476, Yozgat Bozok Üniversitesi), Muhammed Fatih Tabara (0000-0002-7479-5622, Elazığ Eğitim ve Araştırma Hastanesi), Tuba Duygu Yılmaz (0000-0002-0229-7659, Botkin Hospital), Kamer Kaya (0000-0001-8678-5467, Elazığ Eğitim ve Araştırma Hastanesi), Denizhan Danacı Keleş (0000-0003-3854-5922, University Of Medicine 1 Yangon), S Karakas (0000-0002-6393-2636, Fırat University), Düzgün Şimşek (0009-0002-2260-8255, Institute of Mental Health and Hospital), Murad Atmaca (0000-0003-2772-4124, Fırat University)
Year2023
Volume24
Issue2
Pages366-379
Publication date2023-12-03
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueJournal of Ethnicity in Substance Abuse (JOURNAL)
Journal identifiersISSN: 1533-2640 • E-ISSN: 1533-2659
PublisherTaylor & Francis (PUBLISHER • GB)
DOI10.1080/15332640.2023.2278475
PMID38043030
OpenAlexW4389286663
LanguageEN
References cited40

The etiology of addiction has not yet been fully elucidated. The ratio between the length of the second and fourth fingers (2D:4D ratio) has been linked with prenatal androgen concentrations, but also with addictive behvaiors. Aim: The present study aimed to evaluate the differences of 2D:4D ratio of individuals with cannabis and heroin addiction by examining them together with the control group. A total of sixty two male patients (33 opiate use disorder and 29 cannabis use disorder) with substance use disorder and the twenty-nine healthy controls were included in the present investigation. We obtained the lengths of 2D and 4D of the subjects by using sensitive calipers and calculated the 2D:4D. Heroin-addicted patients had lower 2D:4D ratio in in the right hand (significant difference between control group) ( p p = 0.242) and control-cannabis 2D:4D ratios ( p p p p = 1). In conclusion, we suggest that heroin-and cannabis addicted patients seem to have a lower ratio of 2D:4D compared to healthy control subjects. Our findings can be considered promising as to whether prenatal hormonal factors are important in the etiopathogenesis of addiction

Addiction · Cannabis · Digit ratio · Drug · Etiology · Heroin · Heroin addiction · Psychiatry · Significant difference · Testosterone (patch · Clinical Psychology · Medicine · Sexual Differentiation and Disorders · Urologic and reproductive health conditions · Urological Disorders and Treatments · Internal Medicine

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