The Relationship of Tobacco, Alcohol, and Betel Quid with the Formation of Oral Potentially Malignant Disorders

A Community-Based Study from Northeastern Thailand

Bibliographic Data

ID15460663
AuthorsPrangtip Worakhajit (0000-0002-0163-2654, Mahidol University), Pornpoj Fuangtharnthip (0000-0002-8565-7233, Mahidol University), Siribang-on Piboonniyom Khovidhunkit (0000-0002-4496-7964, Mahidol University), Pim Chiewwit (Mahidol University), Boworn Klongnoi (Mahidol University, corresponding author)
Year2021
Volume18
Issue16
Pages8738-8738
Publication date2021-08-19
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph18168738
PMID34444487
OpenAlexW3194749897
LanguageEN
Citations received3
References cited53

This study's objective was to describe the relationship between the main risk factors for oral cancer, including tobacco (in the form of cigarettes, smokeless tobacco (SLT), secondhand smoking (SS)), alcohol, and betel quid (BQ), and the occurrence of oral potentially malignant disorders (OPMDs). A community-based case-control study was conducted with a population of 1448 adults aged 40 years or above in northeastern Thailand. Patients aged 60 years or above (OR 1.79, p p p p < 0.001). Even former users were at risk of developing OPMDs. The synergistic effect between these main risk factors was significantly shown in the group exposed to SLT, SS, BQ, and alcohol. The most potent synergistic effect was found in the group exposed to SLT, BQ and alcohol with the OR = 20.96

Alcohol · Areca · Betel · Biology · Cancer · Environmental health · Population · Risk factor · Smokeless tobacco · Tobacco use · Traditional medicine · Head and Neck Cancer Studies · Medicine · Oral and Maxillofacial Pathology · Oral Health Pathology and Treatment · Internal Medicine

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