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Effect of Carbohydrate-Electrolyte Solution Including Bicarbonate Ion Ad Libitum Ingestion on Urine Bicarbonate Retention during Mountain Trekking

A Randomized, Controlled Pilot Study

Bibliographic Data

ID15460892
AuthorsMasahiro Horiuchi (0000-0001-5784-5694, Mount Fuji Research Institute, corresponding author), Tatsuya Hasegawa (0000-0001-7310-786X, Mount Fuji Research Institute), Hiroshi Nosé (0000-0003-0994-1619, Shinshu University)
Year2021
Volume18
Issue4
Pages1441-1441
Publication date2021-02-04
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph18041441
PMID33557035
OpenAlexW3126511083
LanguageEN
References cited46

We investigated whether bicarbonate ion (HCO 3 - ) in a carbohydrate-electrolyte solution (CE+HCO 3 ) ingested during climbing to 3000 m on Mount Fuji could increase urine HCO 3 - retention. This study was a randomized, controlled pilot study. Sixteen healthy lowlander adults were divided into two groups (six males and two females for each): a tap water (TW) group (0 kcal with no energy) and a CE+HCO3 group. The allocation to TW or CE+HCO3 was double blind. The CE solution contains 10 kcal energy, including Na + (115 mg), K + (78 mg), HCO 3 - (51 mg) per 100 mL. After collecting baseline urine and measuring body weight, participants started climbing while energy expenditure (EE) and heart rate (HR) were recorded every min with a portable calorimeter. After reaching a hut at approximately 3000 m, we collected urine and measured body weight again. The HCO 3 - balance during climbing, measured by subtracting the amount of urine excreted from the amount of fluid ingested, was -0.37 ± 0.77 mmol in the CE+HCO3, which was significantly higher than in the TW (-2.23 ± 0.96 mmol, p 3 - supplementation may increase the bicarbonate buffering system during mountain trekking up to ~3000 m, suggesting a useful solution, at least, in the population of the present study on Mount Fuji

Bicarbonate · Carbohydrate · Electrolyte · Ingestion · Pilot trial · Randomized controlled trial · Sodium bicarbonate · Urine · Adipose Tissue and Metabolism · Chemistry · High Altitude and Hypoxia · Medicine · Muscle metabolism and nutrition · Biochemistry · Internal Medicine

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