Heart Rate Variability and Sympathetic Activity Is Modulated by Very Low-Calorie Ketogenic Diet
Bibliographic Data
| ID | 15463576 |
|---|---|
| Authors | Rita Polito (0000-0003-1313-2574, University of Foggia), Anna Valenzano (0000-0002-9346-4108, University of Foggia), Vincenzo Monda (0000-0002-6083-5814, University of Campania "Luigi Vanvitelli"), Giuseppe Cibelli (0000-0002-5371-2584, University of Foggia), Marcellino Monda (0000-0002-7184-218X, University of Campania "Luigi Vanvitelli"), Giovanni Messina (0000-0002-2414-993X, University of Foggia), Ines Villano (0000-0002-1755-358X, University of Campania "Luigi Vanvitelli"), Antonietta Messina (0000-0001-8343-432X, University of Campania "Luigi Vanvitelli", corresponding author) |
| Year | 2022 |
| Volume | 19 |
| Issue | 4 |
| Pages | 2253-2253 |
| Publication date | 2022-02-16 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph19042253 |
| PMID | 35206443 |
| OpenAlex | W4213341680 |
| Language | EN |
| Citations received | 1 |
| References cited | 30 |
Obesity is characterized by an energy imbalance and by the accumulation of visceral adipose tissue. The energy balance is controlled by a complex set of balanced physiological systems that provide hunger and satiety signals to the brain and regulate the body's ability to consume energy. The central nervous system controls the metabolic state, influencing the activity of other systems and receiving information from them. Heart rate variability (HRV) is the natural variability of the heart rate in response to several factors. HRV is related to the interaction between the SNS and the parasympathetic. In the light of this evidence, the aim of this study is to investigate the possible effects of the two different dietary regimens such as very low-calorie ketogenic diet (VLCKD) vs. low caloric diet (LCD), on the functions of the nervous system, with particular attention to the autonomous control of heart rate variability (HRV). A total of 26 obese subjects underwent diet therapy in order to reduce body weight; they were also randomly divided into two groups: the VLCKD group and the LCD group. Our results showed that in both groups, there is a reduction in heart rate as an indicator of sympathetic activity; we found a statistically significant variation only in the VLCKD group. Therefore, this study supports the notion that the sympathovagal balance can be modulated by a specific diet, but further studies are needed to clarify the molecular pathway undergoing this modulation
Adipose tissue · Autonomic nervous system · Balance (ability · Blood pressure · Calorie · Heart rate · Heart rate variability · Ketogenic Diet · Obesity · Physical medicine and rehabilitation · Sympathetic nervous system · Adipose Tissue and Metabolism · Diet and metabolism studies · Heart Rate Variability and Autonomic Control · Medicine · Endocrinology · Internal Medicine · Physiology
| Unique citing works | 1 |
|---|---|
| Citations per year | 1 |
| Citation span | 2026 - 2026 (1) |
| Citation velocity | current |
| Highly cited | No |
| Citation types | Neutral: 1 |