The Association between Drinking Water Quality and Inflammatory Bowel Disease—A Study in Eastern Croatia
Bibliographic Data
| ID | 15464002 |
|---|---|
| Authors | Dubravka Holik (0000-0003-3409-8029, University of Osijek), Atila Bezdan (0000-0003-3713-3002, University of Novi Sad), Monika Markovıć (0000-0002-8742-6922, University of Osijek, corresponding author), Želimir Orkić (University of Osijek), Andrea Milostić-Srb (0000-0002-4608-8373, University of Osijek), Štefica Mikšić (0000-0003-1199-3768, University of Osijek), Aleksandar Včev (0000-0003-0512-462X, University of Osijek) |
| Year | 2020 |
| Volume | 17 |
| Issue | 22 |
| Pages | 8495-8495 |
| Publication date | 2020-11-16 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | International Journal of Environmental Research and Public Health (JOURNAL) |
| Journal identifiers | ISSN: 1661-7827 • E-ISSN: 1660-4601 |
| Publisher | Multidisciplinary Digital Publishing Institute (PUBLISHER • CH) |
| DOI | 10.3390/ijerph17228495 |
| PMID | 33207850 |
| OpenAlex | W3100115707 |
| Language | EN |
| Citations received | 1 |
The incidence rate of inflammatory bowel disease (IBD) is becoming a global health problem that could be caused by changes in environmental and lifestyle habits. The study aimed to identify the association between the quality of drinking water, i.e., physiochemical and biological aspects of the phenotype and activity of IBD in Eastern Croatia. The study included 312 patients (63.4% ulcerative colitis, UC, and 36.6% Crohn's disease, CD) from the area of Eastern Croatia. The data were collected by questionnaires and the analysis of the water safety, based on 65 samples of drinking water by the patient's water supply method (public supply, rural water supply, and private well). IBD was active in 38.0% patients (34.0% CD and 40.0% UC). Significant differences ( p = 0.001) were observed in the distribution of patients, according to counties in which they lived in. The largest deviation was noted in coliform bacteria, Escherichia coli , and enterococci bacteria, Fe, Al, and nitrate in rural water supply and private wells, although, without significant impact on IBD phenotype and activity. The hazard quotient (HQ) simulations showed that children are a sensitive group, regarding exposure to nitrates in drinking water over a long period of time, so there is a need for further monitoring and analysis of this issue
Bacteria · Biology · Coliform bacteria · Disease · Environmental health · Hazard quotient · Human health · Incidence (geometry · Pathology · Rural area · Ulcerative colitis · Water quality · Water supply · Environmental Science · Gut microbiota and health · Inflammatory Bowel Disease · Medicine · Microscopic Colitis · Ecology · Environmental Engineering · Internal Medicine
| Unique citing works | 1 |
|---|---|
| Citations per year | 1 |
| Citation span | 2025 - 2025 (1) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 1 |