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Factors Associated with Refusal or Discontinuation of Treatment in Patients with Bladder Cancer

A Cohort Population-Based Study in Taiwan

Bibliographic Data

ID15464994
AuthorsNai-Tan Chang (0000-0003-4320-6343, Chang Gung University), Ying‐hsu Chang (0000-0002-7265-6231, Chang Gung University), Yu‐tung Huang (0000-0003-3224-7238, Chang Gung Memorial Hospital), Shu‐Ching Chen (0000-0001-9209-390X, corresponding author), Shu-Ching Chen (0000-0002-7921-1964, Chang Gung University of Science and Technology, corresponding author)
Year2021
Volume18
Issue2
Pages618-618
Publication date2021-01-13
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph18020618
PMID33450864
OpenAlexW3120191031
LanguageEN
References cited2

Cancer treatment causes adverse effects that lead to refusal or discontinuation of treatment. The purposes of this study were to identify 1) the factors associated with and 2) the reasons for refusing and discontinuing treatment in patients with bladder cancer (BC). We conducted a retrospective cohort study in patients diagnosed with BC in Taiwan from 1 January 2014 to 30 June 2019 using a linked cancer registry database. Of the 1247 BC patients in the study cohort, 2.1% reported refusing treatment. Patients with less education and those diagnosed at cancer stage II-IV were more likely to refuse treatment. The major reason for refusing treatment was "patient or the family considered patient's poor physical condition (chronic disease or unstable systemic disease), difficulty in enduring any condition likely to cause physical discomfort from disease treatment". A total of 4.3% of BC patients reported discontinuing treatment. Patients not living in the northern region of Taiwan and those diagnosed at cancer stage II-IV were more likely to terminate treatment before completion. The major reason given for discontinuing treatment was inconvenient transportation. Sufficient social resources and supportive care can help BC patients cope with the physical and psychological burden of treatment

Adverse effect · Bladder cancer · Cancer · Cancer registry · Cancer treatment · Cohort · Cohort study · Discontinuation · Disease · Environmental health · Physical therapy · Population · Retrospective cohort study · Bladder and Urothelial Cancer Treatments · Medicine · Multiple and Secondary Primary Cancers · Urinary and Genital Oncology Studies · Internal Medicine · Pediatrics

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