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Community-Based Ototoxicity Monitoring for Drug-Resistant Tuberculosis in South Africa

An Evaluation Study

Bibliographic Data

ID15465121
AuthorsLucia Jane Stevenson (0000-0003-1472-765X, University of Pretoria, corresponding author), Leigh Biagio-de Jager (0000-0002-5095-8626, University of Pretoria), Marien Alet Graham (0000-0003-4071-9864, University of Pretoria), De Wet Swanepoel (0000-0001-8313-1636, Ear Science Institute Australia)
Year2021
Volume18
Issue21
Pages11342-11342
Publication date2021-10-28
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph182111342
PMID34769860
OpenAlexW3209308370
LanguageEN
Citations received1
References cited25

In response to the drug-resistant tuberculosis (DRTB) ototoxicity burden in South Africa, ototoxicity monitoring has been decentralised, with community health workers (CHWs) acting as facilitators. This study describes a community-based ototoxicity monitoring programme (OMP) for patients with DRTB. Findings are compared to the recommended guidelines for ototoxicity monitoring, the OMP protocol and published studies. This was a retrospective study of longitudinal ototoxicity monitoring of 831 patients with DRTB, using data collected at community-based clinics in the City of Cape Town between 2013 and 2017. Approximately half (46.8%) of the patients had an initial assessment conducted in accordance with the OMP protocol recommendations, and follow-up rates (79.5%) were higher than those of a similar DRTB programme. However, patients in this study were not monitored within the timeframes or with the regularity recommended by the guidelines or the OMP protocol. Extended high-frequency pure-tone audiometry (27.5%) was underutilised by testers and data recording was inconsistent (e.g., 37.7% of patient gender was not recorded by testers). Community-based OMP using CHWs to facilitate monitoring showed improvement over previous hospital-based reports, with more accessible services and higher follow-up rates. However, to improve OMP outcomes, OMP managers should reassess current protocols and data recording practices

Alternative medicine · Environmental health · Family medicine · Ototoxicity · Protocol (science · Tuberculosis · Ear Surgery and Otitis Media · Hearing Loss and Rehabilitation · Hearing, Cochlea, Tinnitus, Genetics · Medicine · Surgery

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Unique citing works1
Citations per year1
Citation span2025 - 2025 (1)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 1

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