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Reliability of a Risk-Factor Questionnaire for Osteoporosis

A Primary Care Survey Study with Dual Energy X-ray Absorptiometry Ground Truth

Bibliographic Data

ID15465131
AuthorsMaria Radeva (Jena University Hospital), Dorothee Predel (Südharz Klinikum), Sven Winzler (Südharz Klinikum), Ulf Teichgräber (0000-0002-4048-3938, Jena University Hospital), Alexander Pfeil (0000-0002-2709-6685, Jena University Hospital), Ansgar Malich (Südharz Klinikum), Ismini Papageorgiou (0000-0001-5810-0483, Jena University Hospital, corresponding author)
Year2021
Volume18
Issue3
Pages1136-1136
Publication date2021-01-28
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph18031136
PMID33525339
OpenAlexW3122057507
LanguageEN
References cited50

(1) Purpose: Predisposing factors to osteoporosis (OP) as well as dual-source x-ray densitometry (DXA) steer therapeutic decisions by determining the FRAX index. This study examines the reliability of a standard risk factor questionnaire in OP-screening. (2) Methods: n = 553 eligible questionnaires encompassed 24 OP-predisposing factors. Reliability was assessed using DXA as a gold standard. Multiple logistic regression and Spearman's correlations, as well as the confounding influence of age and body mass index, were analyzed in SPSS (IBM Corporation, Armonk, NY, USA). (3) Results: Our study revealed low patient self-awareness regarding OP and its risk factors. One out of every four patients reported a positive history for osteoporosis not confirmed by DXA. The extraordinarily high incidence of rheumatoid arthritis and thyroid disorders likely reflect confusion with other diseases or health anxiety. FRAX-determining risk factors such as malnutrition, liver insufficiency, prior fracture without trauma, and glucocorticoid therapy did not correlate with increased OP incidence, altogether demonstrating how inaccurate survey information could influence therapeutic decisions on osteoporosis. (4) Conclusions: Contradictive results and a low level of patient self-awareness suggest a high degree of uncertainty and low reliability of the current OP risk factor survey

Bone mineral · Dual-energy X-ray absorptiometry · FRAX · Incidence (geometry · Osteopenia · Osteoporosis · Osteoporotic fracture · Physical therapy · Risk factor · Bone health and osteoporosis research · Medicine · Meta-analysis and systematic reviews · Vitamin D Research Studies · Internal Medicine

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