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Tuberculosis Co-Infection Is Common in Patients Requiring Hospitalization for Covid-19 in Belarus

Mixed-Methods Study

Bibliographic Data

ID15465946
AuthorsYuliia Sereda (0000-0002-4017-4561, World Health Organization Regional Office for Europe), Oleksandr Korotych (World Health Organization Regional Office for Europe, corresponding author), Dzmitry Klimuk (0000-0002-0222-5583, Republican Scientific and Practical Centre of Pulmonology and Tuberculosis), Dzmitry Zhurkin (Republican Scientific and Practical Centre of Pulmonology and Tuberculosis), Varvara Solodovnikova (0000-0003-1655-4000, Republican Scientific and Practical Centre of Pulmonology and Tuberculosis), Malgorzata Grzemska (World Health Organization Regional Office for Europe), Viatcheslav Grankov (0000-0001-9891-2718, Ministry of Health), Hennadz Hurevich (Republican Scientific and Practical Centre of Pulmonology and Tuberculosis), Askar Yedilbayev (0000-0001-8557-5046, World Health Organization Regional Office for Europe), Alena Skrahina (0000-0002-1460-0272, Republican Scientific and Practical Centre of Pulmonology and Tuberculosis)
Year2022
Volume19
Issue7
Pages4370-4370
Publication date2022-04-05
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph19074370
PMID35410048
OpenAlexW4223555476
LanguageEN
References cited15

A significant drop in tuberculosis (TB) case-finding has been widely reported during the period of the COVID-19 pandemic. To address a decrease in TB notification, Belarus introduced laboratory TB testing in patients with the laboratory-confirmed coronavirus disease 2019 (COVID-19). We conducted a secondary analysis of health records among 844 patients with laboratory-confirmed COVID-19 diagnosis who were admitted to repurposed departments at TB hospitals and who were tested by Xpert MTB/RIF (Cepheid Inc., Sunnyvale, CA, USA) in five Belarus regions between April and October 2021. Quantitative analysis followed by 13 individual interviews with health managers, physicians, and nurses participating in the intervention. Most patients were male (64%) and mean age was 43.5 ± 16 years. One in twenty (n = 47, 5.6%) patients were co-infected with active pulmonary TB, and over one-third of them (n = 18) had rifampicin resistance. In-hospital mortality was comparable in patients with and without TB co-infection (2.1% and 2.3% respectively, p > 0.99). Laboratory TB testing among patients with COVID-19 at repurposed departments of TB hospitals is feasible in Belarus and may improve TB case-finding

Contact tracing · Coronavirus disease 2019 (COVID-19 · Disease · Infectious disease (medical specialty · Pandemic · Pathology · Pulmonary tuberculosis · Rifampicin · Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 · Tuberculosis · COVID-19 Clinical Research Studies · Long-Term Effects of COVID-19 · Medicine · Tuberculosis Research and Epidemiology · Emergency Medicine · Internal Medicine · Pediatrics

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