H-Type Hypertension and C Reactive Protein in Recurrence of Ischemic Stroke

Bibliographic Data

ID15466309
AuthorsQing Zhang (0000-0001-6929-9416, Henan University), De-Xing Qiu (Guangming New District People’s Hospital & Community Health Service Management Center of Guangming Area, Shenzhen 518000, China), Rong-Li Fu (Henan University Huaihe Hospital and Huaihe Clinical Institute), Tian-Fen Xu (Guangzhou Medical University), Mengjuan Jing (0009-0002-4856-5783, Henan University), Meng-Juan Jing (Henan University), Huishan Zhang (0000-0001-5324-9959, Guangzhou Medical University), Hui-Shan Zhang (Guangzhou Medical University), He-Hong Geng (0000-0001-6241-9964, Henan University), Long-Chao Zheng (Guiyang Medical University), Pei-Xi Wang (Guangzhou Medical University, corresponding author)
Year2016
Volume13
Issue5
Pages477-477
Publication date2016-05-07
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph13050477
PMID27164124
OpenAlexW2345830122
LanguageEN
Citations received1
References cited41

Hypertension with high homocysteine (HHcy) (H-type hypertension) and C reactive protein (CRP) can increase the incidence of ischemic stroke. However, it is not clear whether recurrent ischemic stroke (RIS) is related to H-type hypertension and CRP. The present study investigated the correlation of H-type hypertension and CRP level with RIS. Totally, 987 consecutive patients with acute ischemic stroke were recruited in a teaching hospital in Henan province, China during March 2014 to March 2015. The demographic and clinical characteristics and blood biochemical parameters of patients were analyzed. Elevated levels of CRP and homocysteine (Hcy) were defined as >8.2 mg/L and 10 μmol/L, respectively. Among the 987 patients, 234 were RIS. Thirty-eight percent of RIS patients had elevated CRP level and 91.5% of RIS patients had HHcy. In multivariate analysis, adjusted odds ratio (OR) of RIS in patients aged ≥60 years was 1.576 (95% CI: 1.125-2.207), in male patients 1.935 (95% CI: 1.385-2.704), in patients with diabetes 1.463 (95% CI: 1.037-2.064), CRP levels 1.013 (95% CI: 1.006-1.019), simple hypertension 3.370 (95% CI: 1.15-10.183), and H-type hypertension 2.990 (95% CI: 1.176-7.600). RIS was associated with older age, male, diabetes, H-type hypertension and CRP. Controlling H-type hypertension and CRP level may reduce the risk of RIS

Blood pressure · C-reactive protein · Cardiology · Diabetes mellitus · Essential hypertension · Homocysteine · Incidence (geometry · Inflammation · Ischemia · Ischemic stroke · Odds ratio · Stroke (engine · Type 2 diabetes · Type 2 Diabetes Mellitus · Acute Ischemic Stroke Management · Cerebrovascular and Carotid Artery Diseases · Folate and B Vitamins Research · Medicine · Endocrinology · Gastroenterology · Internal Medicine

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